Date published: 2026-6-7

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(±)20-HDoHE (CAS 90906-41-5)

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Alternate Names:
20-hydroxy Docosahexaenoic Acid
Application:
(±)20-HDoHE is an autoxidation product of docosahexaenoic acid
CAS Number:
90906-41-5
Molecular Weight:
344.5
Molecular Formula:
C22H32O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(±)20-HDoHE, cataloged under CAS number 90906-41-5, is a hydroxylated derivative of docosahexaenoic acid (DHA), which is a prominent omega-3 fatty acid extensively found in marine oils. The compound features a hydroxyl group at the 20th carbon in the fatty acid chain, and the (±) prefix indicates the inclusion of both enantiomers of the molecule. This structural modification enhances its role as a lipid mediator, potentially influencing a range of cellular signaling pathways. In research settings, (±)20-HDoHE is particularly valued for its capacity to interact with specific enzymes and receptors that play pivotal roles in cellular processes including inflammatory response modulation and signal transduction related to cell survival and adaptation. Investigations into (±)20-HDoHE′s actions focus on understanding how it affects the production and function of cytokines, growth factors, and other critical mediators of cellular communication. These studies are vital for elucidating the molecular mechanisms by which modifications in fatty acid molecules like DHA can impact cellular functionality and response to physiological stimuli. By exploring the effects of (±)20-HDoHE, researchers aim to gain deeper insights into the complex dynamics of lipid signaling pathways and their influence on maintaining cellular integrity and response capabilities.


(±)20-HDoHE (CAS 90906-41-5) References

  1. Oxylipin diversity in the diatom family Leptocylindraceae reveals DHA derivatives in marine diatoms.  |  Nanjappa, D., et al. 2014. Mar Drugs. 12: 368-84. PMID: 24445306
  2. UHPLC-MS-MS analysis of oxylipins metabolomics components of follicular fluid in infertile individuals with diminished ovarian reserve.  |  Liang, C., et al. 2021. Reprod Biol Endocrinol. 19: 143. PMID: 34521427

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)20-HDoHE, 25 µg

sc-205101
25 µg
$80.00

(±)20-HDoHE, 50 µg

sc-205101A
50 µg
$154.00