(±)-2-Bromopropionic acid (CAS 598-72-1)
QUICK LINKS
(±)-2-Bromopropionic acid is in organic synthesis due to its reactivity as a halogenated carboxylic acid. It is a versatile building block in the preparation of various organic intermediates, such as esters, amides, and other derivatives through substitution reactions. The bromine atom in (±)-2-Bromopropionic acid is labile and can participate in nucleophilic substitution reactions, making it a useful reagent for the introduction of the propionyl group into molecular frameworks. (±)-2-Bromopropionic acid is in the synthesis of α-bromo esters and acids, which are important precursors in the production of gamma-lactones and other cyclic compounds through cyclization reactions. Some also utilize (±)-2-Bromopropionic acid in enantioselective synthesis studies to create chiral molecules by resolving the racemic mixture or by starting with enantiomerically pure substrates.
(±)-2-Bromopropionic acid (CAS 598-72-1) References
- The absence of cerebellar granule cell necrosis in the mouse following L-2-chloropropionic acid administration. | Lock, EA., et al. 2000. Arch Toxicol. 74: 547-54. PMID: 11131035
- 2-Halopropionic acid-induced cerebellar granule cell necrosis in the rat: in vivo and in vitro studies. | Lock, EA., et al. 2001. Neurotoxicology. 22: 363-74. PMID: 11456337
- Helicene-Grafted Silica Nanoparticles Capture Hetero-Double-Helix Intermediates during Self-Assembly Gelation. | Miyagawa, M. and Yamaguchi, M. 2015. Chemistry. 21: 8408-15. PMID: 25958853
- Accelerating chemical reactions by molecular sledding. | Zhang, L., et al. 2017. Chem Commun (Camb). 53: 6331-6334. PMID: 28548153
- Zwitterionic Hydrobromic Acid Carriers for the Synthesis of 2-Bromopropionic Acid from Lactide. | Kehrer, M., et al. 2018. ChemSusChem. 11: 1063-1072. PMID: 29389081
- Synthesis and chromatographic properties of S-(1-carboxyethyl)-L-cysteine and S-(1-carboxypropyl)-L-cysteine. | Blarzino, C., et al. 1987. Ital J Biochem. 36: 1-7. PMID: 3583684
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)-2-Bromopropionic acid, 250 g | sc-237952 | 250 g | $63.00 |