Molecular structure of (±)16-HETE, CAS Number: 128914-46-5
(±)16-HETE (CAS 128914-46-5)
Alternate Names:
(±)16- hydroxy- 5Z, 8Z, 11Z, 14Z- eicosatetraenoic acid
Application:
(±)16-HETE is a racemic version of a minor CYP450 metabolite
CAS Number:
128914-46-5
Molecular Weight:
320.46
Molecular Formula:
C20H32O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Electrolyte and fluid transport in the kidney are regulated partially by arachidonic acid and its metabolites. (±)16-HETE is the racemic version of a minor CYP450 metabolite of arachidonic acid released by the kidney upon angiotensin II stimulation. The biological activity of 16-HETE is stereospecific. 16(R)-HETE dose-dependently stimulates vasodilation of the rabbit kidney, and does not affect perfusion pressure.1 At a concentration of 2 µM the (S)-enantiomer of 16-HETE inhibits proximal tubule ATPase activity by as much as 60%, while the (R)-isomer has negligible effects on ATPase activity.1
(±)16-HETE (CAS 128914-46-5) References
1 Carroll, M.A., Balazy, M., Margiotta, P., et al. Cytochrome P-450-dependent HETEs: Profile of biological activity and stimulation by vasoactive peptides. Am J Physiol 271 R863-R869 (1996).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)16-HETE, 25 µg | sc-220639 | 25 µg | $139.00 | |||
(±)16-HETE, 50 µg | sc-220639A | 50 µg | $265.00 |