(±)15-HEDE (CAS 77159-57-0)

(±)15-HEDE, bearing the CAS number 77159-57-0, is a racemic mixture of 15-hydroxyeicosa-5(Z),8(Z),11(Z),13(E)-tetraenoic acid enantiomers. This chemical is a derivative of arachidonic acid, produced through enzymatic oxidation involving lipoxygenases. The presence of both enantiomers in the racemic mix allows for the exploration of stereochemical influences on biological activity in research settings. In cellular and biochemical studies, (±)15-HEDE has been instrumental in investigating the regulation of signaling pathways that influence cellular responses to oxidative stress and inflammation. The compound operates by modulating the activities of key signaling proteins and enzymes, impacting processes such as the regulation of gene expression, modulation of receptor activity, and alteration in ion channel function. The specific biochemical roles of (±)15-HEDE include its interaction with lipid signaling pathways, which are crucial for understanding how cells adapt to and communicate under various physiological conditions. Research utilizing this compound often focuses on its ability to influence these pathways, providing insights into the complex network of interactions that govern cellular responses and homeostasis. This detailed understanding aids in elucidating the broader implications of lipid mediators in cellular function and response mechanisms across a variety of biological contexts.