Molecular structure of (±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid, CAS Number: 81276-03-1
(±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid (CAS 81276-03-1)
Alternate Names:
(±)14(15)-EET; (±)14(15)-EpETrE; (±)14,15-DiHETrE
Application:
(±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid is a Cox inhibitor
CAS Number:
81276-03-1
Molecular Weight:
320.47
Molecular Formula:
C20H32O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
(±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid stimulates glucagon release from rat pancreatic islets. (±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid inhibits Cox (cyclooxygenase) and platelet aggregation. (±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid inhibits vasopressin response and induces monocyte adhesion to endothelial cells. (±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid inhibits renin release and decreases blood pressure in rats.
(±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid (CAS 81276-03-1) References
- Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension. | Catella, F., et al. 1990. Proc Natl Acad Sci U S A. 87: 5893-7. PMID: 2198572
- Inhibition of cyclooxygenase activity and platelet aggregation by epoxyeicosatrienoic acids. Influence of stereochemistry. | Fitzpatrick, FA., et al. 1986. J Biol Chem. 261: 15334-8. PMID: 3095326
- Epoxyeicosatrienoic acids stimulate glucagon and insulin release from isolated rat pancreatic islets. | Falck, JR., et al. 1983. Biochem Biophys Res Commun. 114: 743-9. PMID: 6411091
Inhibitor of:
Cox.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid, 50 µg | sc-220607 | 50 µg | $74.00 | |||
(±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid, 1 mg | sc-220607A | 1 mg | $835.00 |