(±)13-HDoHE (CAS 90780-53-3)

(±)13-HDoHE, assigned CAS number 90780-53-3, is a hydroxylated derivative of docosahexaenoic acid (DHA), a critical omega-3 fatty acid abundant in marine resources like fish oil. This specific compound features a hydroxyl group positioned on the thirteenth carbon, with the (±) notation indicating that it consists of a racemic mixture containing both enantiomers. In biochemical and molecular research, (±)13-HDoHE is valued for its role as a lipid mediator potentially impacting a variety of cellular signaling pathways. The presence of the hydroxyl group at such a specific position on the fatty acid chain is thought to influence interactions with various enzymes and receptors involved in cellular processes, including those related to inflammation and cell signaling. This compound is particularly noted for its ability to modulate the behavior of cytokines and other signaling molecules, providing insights into the mechanisms through which lipid molecules can influence cellular functions. Research utilizing (±)13-HDoHE focuses on understanding how such modifications in fatty acid molecules affect their biological activities, and how these activities can alter cellular responses to physiological stimuli. This type of research is crucial for advancing our knowledge of the complex interactions within lipid signaling pathways, and for exploring the fundamental roles that such compounds play in cellular dynamics and homeostasis.