Molecular structure of (±)12(13)-EpOME
(±)12(13)-EpOME
Alternate Names:
(±)-Vernolic Acid; iso-Leukotoxin
Application:
(±)12(13)-EpOME is a 12,13-cis epoxide of linoleic acid
Purity:
≥98%
Molecular Weight:
296.44
Molecular Formula:
C18H32O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
12(13)-EpOME is a lipid epoxide that functions as a signaling molecule in cellular processes. 12(13)-EpOME interacts with specific receptors and enzymes to regulate various pathways related to inflammation and immune function. Its mechanism of action includes influencing the production of pro-inflammatory mediators and the activation of immune cells. 12(13)-EpOME may play a role in the regulation of vascular tone and endothelial function. Its interactions with cellular components contribute to the balance of inflammatory and immune responses in experimental models.
(±)12(13)-EpOME References
- Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols. | Frömel, T., et al. 2012. Proc Natl Acad Sci U S A. 109: 9995-10000. PMID: 22665795
- Maximal exercise and plasma cytochrome P450 and lipoxygenase mediators: a lipidomics study. | Gollasch, B., et al. 2019. Physiol Rep. 7: e14165. PMID: 31304687
- Elevated faecal 12,13-diHOME concentration in neonates at high risk for asthma is produced by gut bacteria and impedes immune tolerance. | Levan, SR., et al. 2019. Nat Microbiol. 4: 1851-1861. PMID: 31332384
- A Soluble Epoxide Hydrolase Inhibitor, 1-TrifluoromethoxyPhenyl-3-(1-Propionylpiperidin-4-yl) Urea, Ameliorates Experimental Autoimmune Encephalomyelitis. | Jonnalagadda, D., et al. 2021. Int J Mol Sci. 22: PMID: 33925035
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)12(13)-EpOME, 25 µg | sc-220590 | 25 µg | $46.00 | |||
(±)12(13)-EpOME, 50 µg | sc-220590A | 50 µg | $66.00 |