(±)12(13)-EpOME-d4
Molecular Weight:
300.5
Molecular Formula:
C18H28D4O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Contains four deuterium atoms at the 9, 10, 12, and 13 positions. Intended for use as an internal standard for the quantification of latanoprost by GC- or LC-mass spectrometry (MS). (±)12(13)-EpOME is the 12,13-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst.1 The toxicity and biosynthesis of (±)12(13)-EpOME have not been well differentiated from (±)12(13)-EpOME, but have been presumed to be essentially the same.2 (±)9(10)-EpOME is generated by neutrophils during the oxidative burst.1 Has been recovered from the lungs of hyperoxic rats and from humans with acute respiratory distress syndrome.2
(±)12(13)-EpOME-d4 References
1 Hayakawa, M., Sugiyama, S., Takamura, T., et al. Neutrophils biosynthesize leukotoxin, 9,10-epoxy-12-octadecenoate. Biochem Biophys Res Commun 137 424-430 (1986). 2 Ozawa, T., Hayakawa, M., Takamura, T., et al. Biosynthesis of leukotoxin, 9,10-epoxy-12 octadecenoate, by leukocytes in lung lavages of rat after exposure to hyperoxia. Biochem Biophys Res Commun 134 1071-1078 (1986).Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)12(13)-EpOME-d4, 25 µg | sc-220591 | 25 µg | $100.00 | |||
(±)12(13)-EpOME-d4, 50 µg | sc-220591A | 50 µg | $190.00 |