(±)12-HpETE (CAS 71030-35-8)

(±)12-HpETE, with the CAS number 71030-35-8, is a hydroperoxyeicosatetraenoic acid that plays a critical role in the study of lipid oxidation mechanisms and the complex biology of lipid-derived mediators. As an intermediary metabolite of arachidonic acid produced primarily by the action of 12-lipoxygenase, this compound has been pivotal in biochemical research focused on understanding the oxidative pathways of polyunsaturated fatty acids. The specific actions of (±)12-HpETE include its involvement in the formation of various signaling molecules and its capability to modulate the behavior of cells at the molecular level, particularly in relation to the regulation of inflammatory responses. Research utilizing (±)12-HpETE has provided significant insights into the dynamics of cell signaling pathways influenced by oxidized lipids, highlighting how cells react to oxidative stress and adjust their functional parameters in response. This has been especially useful in fields such as biochemistry and cell biology, where studying the effects of lipid peroxidation products is crucial for mapping out the complex interactions within cellular systems. The compound′s reactive nature and its involvement in forming biologically active molecules make it a valuable tool in the study of lipidomics and the broader scope of cellular response mechanisms to oxidative entities.