(±)12,13-DiHOME-d4
QUICK LINKS
12,13-DiHOME-d4 is a stable isotope-labeled analog of 12,13-DiHOME, a diol metabolite of linoleic acid. It is used as an internal standard in mass spectrometry-based lipidomics to quantify endogenous levels of 12,13-DiHOME in biological samples. 12,13-DiHOME-d4 behaves identically to the unlabeled 12,13-DiHOME in chemical reactions and mass spectrometry detection. 12,13-DiHOME-d4 serves as a tool for researchers studying the metabolism and physiological roles of linoleic acid derivatives, providing precise measurements of 12,13-DiHOME levels in biological systems.12,13-DiHOME-d4 interacts with the same enzymes and transporters as the unlabeled 12,13-DiHOME, enabling researchers to elucidate the metabolic pathways and regulatory mechanisms involving this diol metabolite.
(±)12,13-DiHOME-d4 References
- The G2A receptor (GPR132) contributes to oxaliplatin-induced mechanical pain hypersensitivity. | Hohmann, SW., et al. 2017. Sci Rep. 7: 446. PMID: 28348394
- Elevated faecal 12,13-diHOME concentration in neonates at high risk for asthma is produced by gut bacteria and impedes immune tolerance. | Levan, SR., et al. 2019. Nat Microbiol. 4: 1851-1861. PMID: 31332384
- Production of Hydroxy Fatty Acids, Precursors of γ-Hexalactone, Contributes to the Characteristic Sweet Aroma of Beef. | Ueda, S., et al. 2022. Metabolites. 12: PMID: 35448519
- Linoleic acid and linoleate diols in neonatal cord blood influence birth weight. | Umeda, N., et al. 2022. Front Endocrinol (Lausanne). 13: 986650. PMID: 36093109
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)12,13-DiHOME-d4, 25 µg | sc-220589 | 25 µg | $86.00 | |||
(±)12,13-DiHOME-d4, 50 µg | sc-220589A | 50 µg | $163.00 |