(±)11(12)-EET methyl ester (CAS 73799-06-1)

(±)11(12)-EET methyl ester, with CAS number 73799-06-1, is a synthetic derivative of epoxyeicosatrienoic acids (EETs), specifically the 11,12-EET, which is one of the epoxy metabolites formed from arachidonic acid through the action of cytochrome P450 enzymes. This compound is chemically modified into a methyl ester to enhance its stability and solubility for use in biological research. EETs like (±)11(12)-EET methyl ester are crucial for studying cellular signaling pathways, as they play significant roles in modulating various physiological processes. In research settings, this compound has been used to explore its effects on intracellular signaling that relate to the regulation of vascular tone, inflammation, and cellular proliferation. The methyl ester form allows easier handling and better delivery into cells for in vitro studies, where its impact on specific signaling molecules or pathways can be assessed. By applying (±)11(12)-EET methyl ester in experimental models, researchers can dissect the complex interactions of EETs with cellular receptors, ion channels, and other regulatory proteins. This informs a broader understanding of how such lipid mediators contribute to cellular homeostasis and response mechanisms, which is vital for advancing knowledge in biochemistry and cell biology, particularly in the areas of lipid signaling and metabolic regulation.