Molecular structure of (±)11-HETE, CAS Number: 73804-65-6
(±)11-HETE (CAS 73804-65-6)
Application:
(±)11-HETE is one of six monohydroxy fatty acids produced via non-enzymatic oxidation of arachidonic acid
CAS Number:
73804-65-6
Purity:
≥98%
Molecular Weight:
320.5
Molecular Formula:
C20H32O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(±)11-HETE is one of the six monohydroxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid. Using chiral phase HPLC, the individual R and S isomers of racemic HETEs have been separated and identified. The racemic HETEs have been quantified as an index of lipid peroxidation using GC/MS.
(±)11-HETE (CAS 73804-65-6) References
- Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-(R)-hete. | Rowlinson, SW., et al. 2000. J Biol Chem. 275: 6586-91. PMID: 10692466
- Effect of Glutamate and Ionomycin on the Release of Arachidonic Acid, Prostaglandins and HETEs from Cultured Neurons and Astrocytes. | Oomagari, K., et al. 1991. Eur J Neurosci. 3: 928-939. PMID: 12106250
- Obesity is positively associated with arachidonic acid-derived 5- and 11-hydroxyeicosatetraenoic acid (HETE). | Pickens, CA., et al. 2017. Metabolism. 70: 177-191. PMID: 28403941
- Cord blood eicosanoid signatures and newborn gestational age. | Gouveia-Figueira, S., et al. 2017. Prostaglandins Other Lipid Mediat. 133: 123-127. PMID: 28736329
- 15-Hydroxy-5,8,11,13-eicosatetraenoic acid inhibits human vascular cyclooxygenase. Potential role in diabetic vascular disease. | Setty, BN. and Stuart, MJ. 1986. J Clin Invest. 77: 202-11. PMID: 3080473
- Arachidonic acid-derived hydroxyeicosatetraenoic acids are positively associated with colon polyps in adult males: a cross-sectional study. | Austin Pickens, C., et al. 2019. Sci Rep. 9: 12033. PMID: 31427689
- Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury via modulating arachidonic acid metabolism. | Wang, W., et al. 2021. Biomed Pharmacother. 134: 111165. PMID: 33370633
- [Arachidonic acid Alox15/12-HETE signaling inhibits vascular calcification]. | Han, YC., et al. 2021. Sheng Li Xue Bao. 73: 571-576. PMID: 34405213
- Profiling oxylipins released from human platelets activated through the GPVI collagen receptor. | Turnbull, RE., et al. 2022. Prostaglandins Other Lipid Mediat. 158: 106607. PMID: 34942378
- Plasma and bronchoalveolar lavage fluid oxylipin levels in experimental porcine lung injury. | Larsson, N., et al. 2022. Prostaglandins Other Lipid Mediat. 160: 106636. PMID: 35307566
- INTERCEPT Pathogen Reduction in Platelet Concentrates, in Contrast to Gamma Irradiation, Induces the Formation of trans-Arachidonic Acids and Affects Eicosanoid Release during Storage. | Leitner, GC., et al. 2022. Biomolecules. 12: PMID: 36139096
- [Identification of 11-HETE in the rat brain and its relevancy to ischemic cerebral edema]. | Usui, M., et al. 1985. No To Shinkei. 37: 295-301. PMID: 3925971
- Characterization of 11-HETE and 15-HETE, together with prostacyclin, as major products of the cyclooxygenase pathway in cultured rat aorta smooth muscle cells. | Bailey, JM., et al. 1983. J Lipid Res. 24: 1419-28. PMID: 6418841
- Biosynthesis, structure and biological activity of hydroxyeicosatetraenoic acids in Hydra vulgaris. | Di Marzo, V., et al. 1993. Biochem J. 295 (Pt 1): 23-9. PMID: 8216222
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)11-HETE, 25 µg | sc-204970 | 25 µg | $98.00 | |||
(±)11-HETE, 50 µg | sc-204970A | 50 µg | $186.00 |