Date published: 2026-5-24

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(±)11-HEPE (CAS 99217-78-4)

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Alternate Names:
(±)11-Hydroxy-5Z,8Z,12E,14Z,17Z-eicosapentaenoic acid
Application:
(±)11-HEPE is an oxylipin
CAS Number:
99217-78-4
Purity:
≥98%
Molecular Weight:
318.5
Molecular Formula:
C20H30O3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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11-HEPE is involved in the regulation of inflammation and immune response. It functions as a signaling molecule that modulates the activity of immune cells, particularly in resolving inflammation. At the molecular level, 11-HEPE interacts with specific receptors on immune cells, leading to the inhibition of pro-inflammatory pathways and the promotion of anti-inflammatory processes. (±)11-Hepe plays a role in the resolution of inflammation by regulating the production of inflammatory mediators and promoting the clearance of inflammatory cells from the site of inflammation. 11-HEPE may influence the production of specialized pro-resolving mediators, contributing to the overall resolution of inflammation. Its mechanism of action involves the modulation of various signaling pathways within immune cells, ultimately leading to the dampening of inflammatory responses and the promotion of tissue repair processes.


(±)11-HEPE (CAS 99217-78-4) References

  1. Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain.  |  Madore, C., et al. 2020. Nat Commun. 11: 6133. PMID: 33257673

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)11-HEPE, 25 µg

sc-204969
25 µg
$190.00

(±)11-HEPE, 50 µg

sc-204969A
50 µg
$363.00