Date published: 2026-4-24

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(±)11,12-DHET

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Alternate Names:
(±)11(12)-DiHET; (±)11,12-dihydroxy-5Z,8Z,14Z-eicosatrienoic acid; (±)11,12-DiHETrE
Molecular Weight:
338.5
Molecular Formula:
C20H34O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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11,12-DHET is involved in the regulation of vascular tone and blood pressure. It acts as an epoxyeicosatrienoic acid (EET) metabolite, which is produced by the metabolism of arachidonic acid by cytochrome P450 epoxygenases. 11,12-DHET is known to have vasodilatory effects, contributing to the regulation of blood flow and vascular function. It functions by modulating potassium channels in vascular smooth muscle cells, leading to hyperpolarization and relaxation of the blood vessels. (±)11,12-Dhet plays a role in the maintenance of cardiovascular homeostasis. Its mechanism of action involves the interaction with specific cellular signaling pathways and ion channels, influencing vascular tone and blood pressure regulation.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)11,12-DHET, 25 µg

sc-220577
25 µg
$154.00

(±)11,12-DHET, 50 µg

sc-220577A
50 µg
$294.00