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11,12-DHET is involved in the regulation of vascular tone and blood pressure. It acts as an epoxyeicosatrienoic acid (EET) metabolite, which is produced by the metabolism of arachidonic acid by cytochrome P450 epoxygenases. 11,12-DHET is known to have vasodilatory effects, contributing to the regulation of blood flow and vascular function. It functions by modulating potassium channels in vascular smooth muscle cells, leading to hyperpolarization and relaxation of the blood vessels. (±)11,12-Dhet plays a role in the maintenance of cardiovascular homeostasis. Its mechanism of action involves the interaction with specific cellular signaling pathways and ion channels, influencing vascular tone and blood pressure regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(±)11,12-DHET, 25 µg | sc-220577 | 25 µg | $154.00 | |||
(±)11,12-DHET, 50 µg | sc-220577A | 50 µg | $294.00 |