Molecular structure of (+)-α-Tocopherol, CAS Number: 59-02-9
(+)-α-Tocopherol (CAS 59-02-9)
Alternate Names:
D-α-Tocopherol; Vitamin E; 2,5,7,8-Tetramethyl-2-(4′,8′,12′-trimethyltridecyl)-6-chromanol; 5,7,8-Trimethyltocol; D-α-Tocopherol
Application:
(+)-α-Tocopherol is a fat-soluble antioxidant
CAS Number:
59-02-9
Molecular Weight:
430.71
Molecular Formula:
C29H50O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
This compound contains a mixture of isomers that is a type of vitamin E. It is believed that (+)-α-Tocopherol acts as an antioxidant, scavenging free radicals and preventing them from causing oxidative damage to cells. It is also thought to be involved in the regulation of gene expression and to play a role in immune system function.
(+)-α-Tocopherol (CAS 59-02-9) References
- Efficacy of dietary D-alpha-tocopherol and DL-alpha-tocopheryl acetate for weanling pigs. | Chung, YK., et al. 1992. J Anim Sci. 70: 2485-92. PMID: 1506309
- Effects of d-alpha-tocopherol supplementation on experimentally induced primate atherosclerosis. | Verlangieri, AJ. and Bush, MJ. 1992. J Am Coll Nutr. 11: 131-8. PMID: 1578087
- Spectroscopic studies of D-alpha-tocopherol concentration-induced transformation in egg phosphatidylcholine vesicles. | Dwiecki, K., et al. 2007. Cell Mol Biol Lett. 12: 51-69. PMID: 17124545
- Effects of oral micellized natural vitamin E (D-α-tocopherol) v. synthetic vitamin E (DL-α-tocopherol) in feed on α-tocopherol levels, stereoisomer distribution, oxidative stress and the immune response in piglets. | Amazan, D., et al. 2014. Animal. 8: 410-9. PMID: 24534689
- A Comparison of Natural (D-α-tocopherol) and Synthetic (DL-α-tocopherol Acetate) Vitamin E Supplementation on the Growth Performance, Meat Quality and Oxidative Status of Broilers. | Cheng, K., et al. 2016. Asian-Australas J Anim Sci. 29: 681-8. PMID: 26954216
- Kinetics of D-alpha-tocopherol in a water soluble base in man. | Bateman, NE. and Uccellini, DA. 1985. J Pharm Pharmacol. 37: 728-9. PMID: 2867143
- Tandem mass spectrometry in vitamin E analysis. | Walton, TJ., et al. 1988. Biomed Environ Mass Spectrom. 16: 289-98. PMID: 3242680
- Effect of formulation on the bioavailability of retinol, D-alpha-tocopherol and riboflavine. | Bateman, NE. and Uccellini, DA. 1984. J Pharm Pharmacol. 36: 461-4. PMID: 6146692
- Modulation of activator protein-1 (AP-1) transcription factor and protein kinase C by hydrogen peroxide and D-alpha-tocopherol in vascular smooth muscle cells. | Stäuble, B., et al. 1994. Eur J Biochem. 226: 393-402. PMID: 8001557
- d-alpha-Tocopherol inhibits low density lipoprotein induced proliferation and protein kinase C activity in vascular smooth muscle cells. | Ozer, NK., et al. 1993. FEBS Lett. 322: 307-10. PMID: 8486164
- Bioavailability of alpha-tocopherol fed with retinol and relative bioavailability of D-alpha-tocopherol or DL-alpha-tocopherol acetate. | Eicher, SD., et al. 1997. J Dairy Sci. 80: 393-9. PMID: 9058282
- Protective effect against sunburn of combined systemic ascorbic acid (vitamin C) and d-alpha-tocopherol (vitamin E). | Eberlein-König, B., et al. 1998. J Am Acad Dermatol. 38: 45-8. PMID: 9448204
- Prevention of diabetes-induced abnormal retinal blood flow by treatment with d-alpha-tocopherol. | Kunisaki, M., et al. 1998. Biofactors. 7: 55-67. PMID: 9523029
Inhibitor of:
βA1/3-crystallin, γC-crystallin, γE-crystallin, γF-crystallin, 4930420K17Rik, 8-oxoG DNA Lesion, AIFL, AK2, APEH, BACH2, C20orf103, C8A, CBWD6, CCDC162, CHIC2, E330021D16Rik, ERAB, Fibrinogen γ, GADD 153, L-Glycerol-3-Phosphate Oxidase, MPV17L, MPV17L2, NLF1, OSGIN2, p60 Mitochondrial Marker, RBP2, RD3, Romo1, SPACA7, SPATA25, TXNDC9, and VDUP1.Activator of:
β2-crystallin, β3-crystallin, βA3-crystallin, γ2-Syntrophin, γN-crystallin, γS-crystallin, ACAD-9, AIFL, AKR1A1, AKR7A3, ALKBH3, ALOXE3, apoH, apoO, ARMD8, Aspergillus, Benzo[a]pyrene, BPY2, C20orf111, C20orf165, C20orf79, C4BPα, C9orf21, CD209d, CH25H, CHCHD4, CLN3, COQ10A, COQ10B, COQ2, COQ4, COQ5, cortexin 3, COX11, CRALBP, CRALBPL, CRBP I, CRBP II, CrxOS, CSB, CTH, CYB561D1, CYB5R3, CYB5RL, CYBASC3, CYHR1, DECR1, DHRS7, DNA pol μ, DnaJB8, DnaJC28, DPEP1, DRP2, Endothelial Lipase, Ero1-Lβ, ERp19, ESD, ETHE1, FAM213A, FAP, FEN-1, FIC1, Filaggrin 2, FLJ34931_BC027072, galectin-7, GPx-3, GPx-8, Grx1, GRXCR1, GSH-1, GSS, GSTK1, Hep C NS4, Hep C NS5a, HHIPL2, hornerin, HPPD, HRSP12, IgG2, Influenza B NA, ING1, K12, KRTAP17-1, KRTAP19-3, KSP37, Ku70, Lce1j, Lipoic Acid, Loricrin, LPO, LRAT, MCART2, Mitochondrial CysRs, MOCS3, MP19, MUTYH, NAGLU, Natural Killer Cell, NCB5OR, NNT, NPAL2, NQO1, Nrl, ODF3B, OPLAH, OR10K2, OR1C1, OR2L2, OR6K6, PC-LKC, PEAR1, Peroxin 19, Pet117, PGAM5, PGRMC1, PGs2_5730494M16Rik, PIWIL3, PLAP, PNKD, PNPLA1, PON1, PPM1N, PQLC1, PRCD, PROSC, PRX2, PYROXD2, R2, RBM Y chromosome, RBMY1A1, RBMY1F, RDH5, RDH7, retbindin, retinitis pigmentosa 1, RGPD7, ROPN1, RP1L1, RPE, RPE65, RPGR, SDHD, SEC14L2, SELENBP1, Selenium, Selenoprotein K, Selenoprotein M marker, Selenoprotein N, Selenoprotein P, Selenoprotein R, Selenoprotein T, SEPHS2, SLC22A12, SMCP, SOCS-7, SOD-3, SPATA16, SPATA18, SPATA25, SPATA9, SPERT, SPRR2E, Sptrx-2, SPTRX-3, Stabilin-1, STEAP, Sulfiredoxin, SUSD5, Tβ-4, Tafazzin, TCP11, TMEM249, Tom6, tPA, TR2IT1, TRAP-1, TRP14, TSARG1, TTP-α, TULP1, TXNDC15, vanin-1, XRCC1, XRCC2, XRN2, XRRA1, and ZDHHC8.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-α-Tocopherol, 10 g | sc-214454 | 10 g | $42.00 | |||
(+)-α-Tocopherol, 25 g | sc-214454A | 25 g | $61.00 | |||
(+)-α-Tocopherol, 100 g | sc-214454B | 100 g | $138.00 |