Date published: 2025-11-23

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PLEKHQ1 Antibody (SS-23): sc-100412

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Datasheets
  • PLEKHQ1 Antibody (SS-23) is a mouse monoclonal IgG1 κ PLEKHQ1 antibody, cited in 1 publications, provided at 100 µg/ml
  • raised against recombinant PLEKHQ1 of human origin
  • recommended for detection of PLEKHQ1 of human origin by WB, IP and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for PLEKHQ1 Antibody (SS-23). This work is in progress.

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PLEKHQ1 Antibody (SS-23) is a mouse monoclonal IgG1 kappa light chain antibody that detects PLEKHQ1 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-PLEKHQ1 antibody (SS-23) is available as a non-conjugated format. PLEKHQ1, also known as pleckstrin homology domain containing, family Q member 1, or PLEKHO2, is a 490 amino acid protein that plays a crucial role in mediating protein-protein and protein-lipid interactions due to its pleckstrin homology (PH) domain. This domain is essential for various cellular processes, including signal transduction and membrane trafficking, making PLEKHQ1 important for maintaining cellular homeostasis and responding to external stimuli. The gene encoding PLEKHQ1 is located on chromosome 15, which is significant as this location is associated with several genetic disorders, including Angelman and Prader-Willi syndromes, highlighting PLEKHQ1′s importance in human health. Additionally, chromosome 15 contains various genes responsive to environmental factors, such as the plant extract formulation Circulat, which aims to mitigate the onset of type 2 diabetes. Understanding PLEKHQ1′s function and interactions can provide insights into disease mechanisms and potential therapeutic targets.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

PLEKHQ1 Antibody (SS-23) References:

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.  |  Strausberg, RL., et al. 2002. Proc Natl Acad Sci U S A. 99: 16899-903. PMID: 12477932
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs.  |  Ota, T., et al. 2004. Nat Genet. 36: 40-5. PMID: 14702039
  3. Analysis of the DNA sequence and duplication history of human chromosome 15.  |  Zody, MC., et al. 2006. Nature. 440: 671-5. PMID: 16572171
  4. Effective gene therapy in an authentic model of Tay-Sachs-related diseases.  |  Cachón-González, MB., et al. 2006. Proc Natl Acad Sci U S A. 103: 10373-10378. PMID: 16801539
  5. Molecular epigenetics of Angelman syndrome.  |  Lalande, M. and Calciano, MA. 2007. Cell Mol Life Sci. 64: 947-60. PMID: 17347796
  6. [The Prader-Willi syndrome].  |  Diene, G., et al. 2007. Ann Endocrinol (Paris). 68: 129-37. PMID: 17499572
  7. Analysis of effects of the herbal preparation Circulat on gene expression levels in cultured human fibroblasts.  |  Antoshechkin, A., et al. 2007. Phytother Res. 21: 777-89. PMID: 17514633
  8. Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes.  |  Makoff, AJ. and Flomen, RH. 2007. Genome Biol. 8: R114. PMID: 17573966

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

PLEKHQ1 Antibody (SS-23)

sc-100412
100 µg/ml
$316.00

For Western Blot, is it recommended to use denatured or non-denatured conditions with PLEKHQ1 (SS-23): sc-100412 antibody?

Asked by: Randy McDonald
Thank you for your question. We recommend this antibody for use in denatured Western Blot conditions. It has not been validated for use in non-denatured conditions. Please contact our Technical Service Department for further details or inquiries.
Answered by: Technical Support
Date published: 2017-03-27
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Rated 5 out of 5 by from Good for Western BlotThis antibody detects a band at the expected isoform molecular weights in HeLa, TT, and Jurkat whole cell lysates. -SCBT QC
Date published: 2023-09-14
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PLEKHQ1 Antibody (SS-23) is rated 4.5 out of 5 by 2.
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