Molecular structure of Pisiferic Acid, CAS Number: 67494-15-9
Pisiferic Acid (CAS 67494-15-9)
CAS Number:
67494-15-9
Molecular Weight:
316.44
Molecular Formula:
C20H28O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Pisiferic acid, also known as 2,4,6,8-tetramethyl-2-octadecenoic acid or 18:4(2,4,6,8), is a naturally occurring polyunsaturated fatty acid found in the seed oils of specific plants, including the pisifera tree. With a lengthy chain of 18 carbon atoms and four double bonds, it serves as a prominent component in various plant oils. Although the precise mechanism of action of pisiferic acid is not yet fully elucidated, it is believed to function by inhibiting the production of pro-inflammatory cytokines, such as TNF-α and IL-6, while activating the production of anti-inflammatory cytokines like IL-10. Furthermore, it is thought to modulate the activity of specific enzymes like cyclooxygenase-2 (COX-2).
Pisiferic Acid (CAS 67494-15-9) References
- Syntheses of carnosic acid and carnosol, anti-oxidants in Rosemary, from pisiferic acid, the major constituent of Sawara. | Tada, M., et al. 2010. Chem Pharm Bull (Tokyo). 58: 27-9. PMID: 20045961
- Pisiferdiol and pisiferic acid isolated from Chamaecyparis pisifera activate protein phosphatase 2C in vitro and induce caspase-3/7-dependent apoptosis via dephosphorylation of Bad in HL60 cells. | Aburai, N., et al. 2010. Phytomedicine. 17: 782-8. PMID: 20153620
- Effect of pisiferic acid and its derivatives on cytotoxicity macromolecular synthesis and DNA polymerase alpha of HeLa cells. | Kobayashi, K., et al. 1989. Int J Biochem. 21: 463-8. PMID: 2474465
- Overcoming the plasticity of plant specialized metabolism for selective diterpene production in yeast. | Ignea, C., et al. 2017. Sci Rep. 7: 8855. PMID: 28821847
- New Labdanes with Antimicrobial and Acaricidal Activity: Terpenes of Callitris and Widdringtonia (Cupressaceae). | Sadgrove, NJ., et al. 2020. Antibiotics (Basel). 9: PMID: 32290471
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pisiferic Acid, 100 mg | sc-474070 | 100 mg | $449.00 |