Molecular structure of Pirlimycin hydrochloride (Mixture of Diastereomers), CAS Number: 78822-40-9
Pirlimycin hydrochloride (Mixture of Diastereomers) (CAS 78822-40-9)
Alternate Names:
Pirlimycin hydrochloride (Mixture of Diastereomers) also known as (cis)-!Methyl 7-Chloro-6,7,8-trideoxy-6-[[(4-ethyl-2-piperidinyl)carbonyl]amino]-1 -thio-L-threo-α-D-galactoοctopyranoside! Hydrochloride; Pirsue; U 57930E
Application:
Pirlimycin hydrochloride (Mixture of Diastereomers) is a semi-synthetic lincosaminide antibiotic and a structural analog of Clindamycin
CAS Number:
78822-40-9
Purity:
≥95%
Molecular Weight:
447.42
Molecular Formula:
C17H31ClN2O5S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Pirlimycin Hydrochloride is a mixture of diastereomers. In various research applications, this compound is of interest due to its specific interaction with bacterial ribosomes, which can be studied in biochemical assays to understand ribosomal function and protein synthesis. It is often used as a standard or reference material in analytical chemistry to calibrate instruments or to develop new analytical methods, ensuring accuracy and precision in the detection of similar compounds. Pirlimycin Hydrochloride can also be a subject in studies focusing on the resistance mechanisms bacteria may develop, providing insights into the molecular evolution of such traits. In different ecosystems Pirlimycin Hydrochloride can be monitored, contributing to the understanding of the environmental impact and behavior of similar compounds. Furthermore, it plays a role in biodegradation studies, where researchers investigate the breakdown products and pathways of lincosamide compounds.
Pirlimycin hydrochloride (Mixture of Diastereomers) (CAS 78822-40-9) References
- Environmental gram-positive mastitis treatment: in vitro sensitivity and bacteriologic cure. | Cattell, MB., et al. 2001. J Dairy Sci. 84: 2036-43. PMID: 11573783
- Efficacy of extended pirlimycin hydrochloride therapy for treatment of environmental Streptococcus spp and Staphylococcus aureus intramammary infections in lactating dairy cows. | Gillespie, BE., et al. 2002. Vet Ther. 3: 373-80. PMID: 12584673
- Efficacy of extended pirlimycin therapy for treatment of experimentally induced Streptococcus uberis intramammary infections in lactating dairy cattle. | Oliver, SP., et al. 2003. Vet Ther. 4: 299-308. PMID: 15136992
- Influence of prepartum pirlimycin hydrochloride or penicillin-novobiocin therapy on mastitis in heifers during early lactation. | Oliver, SP., et al. 2004. J Dairy Sci. 87: 1727-31. PMID: 15453485
- Factors affecting cure and somatic cell count after pirlimycin treatment of subclinical mastitis in lactating cows. | Deluyker, HA., et al. 2005. J Dairy Sci. 88: 604-14. PMID: 15653527
- Effect of prepartum intramammary treatment with pirlimycin hydrochloride on prevalence of early first-lactation mastitis in dairy heifers. | Middleton, JR., et al. 2005. J Am Vet Med Assoc. 227: 1969-74. PMID: 16379636
- Intramammary infections in heifers during early lactation following intramammary infusion of pirlimycin hydrochloride or penicillin-novobiocin at the first milking after parturition. | Oliver, SP., et al. 2007. J Dairy Res. 74: 211-7. PMID: 17227598
- Effect of precalving intramammary treatment with pirlimycin in nulliparous Holstein heifers. | Roy, JP., et al. 2007. Can J Vet Res. 71: 283-91. PMID: 17955903
- Relationship between results of in vitro susceptibility tests and outcomes following treatment with pirlimycin hydrochloride in cows with subclinical mastitis associated with gram-positive pathogens. | Apparao, D., et al. 2009. J Am Vet Med Assoc. 234: 1437-46. PMID: 19480625
- Effect of lactation therapy on Staphylococcus aureus transmission dynamics in two commercial dairy herds. | Barlow, JW., et al. 2013. BMC Vet Res. 9: 28. PMID: 23398676
- Comparisons of milk quality on North Carolina organic and conventional dairies. | Mullen, KA., et al. 2013. J Dairy Sci. 96: 6753-62. PMID: 23932134
- The effect of intramammary pirlimycin hydrochloride on the fecal microbiome of early-lactation heifers. | Adkins, PRF., et al. 2020. J Dairy Sci. 103: 3459-3469. PMID: 32037172
- Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. | Birkenmeyer, RD., et al. 1984. J Med Chem. 27: 216-23. PMID: 6363698
- In vitro activity of U-57930E against anaerobic bacteria and its comparison with clindamycin, ampicillin, carbenicillin and tetracycline. | Qadri, SM., et al. 1983. J Antibiot (Tokyo). 36: 42-6. PMID: 6678915
- In vitro activity of U-57930E, a new clindamycin analog, against aerobic gram-positive bacteria. | Ahonkhai, VI., et al. 1982. Antimicrob Agents Chemother. 21: 902-5. PMID: 7114838
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pirlimycin hydrochloride (Mixture of Diastereomers), 500 µg | sc-212565 | 500 µg | $413.00 | |||
Pirlimycin hydrochloride (Mixture of Diastereomers), 5 mg | sc-212565A | 5 mg | $2601.00 |