Molecular structure of Piperafizine A, CAS Number: 130603-59-7
Piperafizine A (CAS 130603-59-7)
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Application:
Piperafizine A is a methylated diketopiperazine
CAS Number:
130603-59-7
Purity:
>99%
Molecular Weight:
304.3
Molecular Formula:
C19H16N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Piperafizine A is a diketopiperazine compound isolated from Streptoverticillium aspergilloides. Piperafizine A is described to potentiate the cytotoxicity induced by Vincristine (sc-201434) against Moser cells, VCR-sensitive and VCR-resistant P388 cells.
Piperafizine A (CAS 130603-59-7) References
- Potentiation of vincristine cytotoxicity by rubiginone B1 and piperafizine A in human Moser and K562 cells--mode of action. | Ogasawara, M., et al. 1992. J Antibiot (Tokyo). 45: 129-32. PMID: 1548183
- Piperafizines A and B, potentiators of cytotoxicity of vincristine. | Kamei, H., et al. 1990. J Antibiot (Tokyo). 43: 1018-20. PMID: 2211350
- Antiproliferative and antiplasmodial compounds from selected Streptomyces species. | Harinantenaina Rakotondraibe, L., et al. 2015. Bioorg Med Chem Lett. 25: 5646-9. PMID: 26508548
- Design, synthesis and cytotoxic activities of novel 2,5-diketopiperazine derivatives. | Liao, SR., et al. 2016. Eur J Med Chem. 121: 500-509. PMID: 27318124
- One-step Bio-guided Isolation of Secondary Metabolites from the Endophytic Fungus Penicillium crustosum Using High-resolution Semi-preparative HPLC. | Alfattani, A., et al. 2024. Comb Chem High Throughput Screen. 27: 573-583. PMID: 37424340
- Site selective synthesis of cytotoxic 1,3,6-trisubstituted 3,6-diunsaturated (3Z,6Z)-2,5-diketopiperazines via a one-pot multicomponent method | Sheng-Rong Liao a †, Li-Juan Du b †, Xiao-Chu Qin c, Liang Xu d, Jun-Feng Wang a, Xue-Feng Zhou a, Zheng-Chao Tu c, Juan Li b, Yong-Hong Liu a. 2016. Tetrahedron. 72: 1051-1057.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Piperafizine A, 1 mg | sc-202290 | 1 mg | $231.00 |