Pinch-1 Antibody (49): sc-136299
- Pinch-1 Antibody (49) is a mouse monoclonal IgG2a, cited in 1 publications, provided at 50 µg/0.5 ml
- raised against amino acids 120-220 of Pinch-1 of human origin
- recommended for detection of Pinch-1 of mouse, rat and human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Pinch-1 Antibody (49). This work is in progress.
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Pinch-1 Antibody (49) is a mouse monoclonal IgG2a antibody that detects Pinch-1 in mouse, rat, and human samples through applications such as western blotting (WB) and immunoprecipitation (IP). Pinch-1 is a crucial focal adhesion protein that plays a significant role in the ILK-PINCH complex, which is integral to growth factor and integrin signaling pathways. Pinch-1 is essential for various cellular processes, including differentiation, proliferation, and survival, acting as an effector of integrin and growth factor signaling. Located primarily in the cytoplasm, Pinch-1 is expressed in most tissues and features a unique structure comprising five LIM domains, a nuclear localization signal, and a nuclear export signal, which are vital for function and interaction with other proteins. Notably, the PINCH-1/ILK complex is regulated by PINCH-2, which also associates with ILK, highlighting the intricate regulatory mechanisms that govern cellular signaling pathways. Anti-Pinch-1 antibody (49) effectively targets this focal adhesion protein, making Pinch-1 (49) antibody an invaluable tool for researchers studying cellular dynamics and signaling in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pinch-1 Antibody (49) | sc-136299 | 50 µg/0.5 ml | $316.00 |