Molecular structure of Pinaverium Bromide, CAS Number: 53251-94-8
Pinaverium Bromide (CAS 53251-94-8)
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Alternate Names:
4-[(2-Bromo-4,5-dimethoxyphenyl)methyl]-4-[2-[2-(6,6-dimethylbicyclo[3.1.1]-hept-2-yl)ethoxy]ethyl]morpholinium Bromide; LAT-1717; Dicetel
Application:
Pinaverium Bromide is a spasmolytic agent
CAS Number:
53251-94-8
Molecular Weight:
591.42
Molecular Formula:
C26H41Br2NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Pinaverium bromide is a compound that was synthetically developed in the 1970s. It is a quaternary ammonium compound. The main mechanism of action of pinaverium bromide is believed to involve the inhibition of acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine. The biochemical activity of Pinaverium Bromide offers insights into calcium signaling pathways and smooth muscle physiology. Research on this compound can contribute to a broader understanding of the regulation of smooth muscle contraction and the role of calcium ions in cellular signaling.
Pinaverium Bromide (CAS 53251-94-8) References
- Effect of pinaverium bromide on stress-induced colonic smooth muscle contractility disorder in rats. | Dai, Y., et al. 2003. World J Gastroenterol. 9: 557-61. PMID: 12632518
- Action of pinaverium bromide, a calcium-antagonist, on gastrointestinal motility disorders. | Christen, MO. 1990. Gen Pharmacol. 21: 821-5. PMID: 2177709
- Effect of antispasmodic agents, alone or in combination, in the treatment of Irritable Bowel Syndrome: systematic review and meta-analysis. | Martínez-Vázquez, MA., et al. 2012. Rev Gastroenterol Mex. 77: 82-90. PMID: 22672854
- Determination of Pinaverium Bromide in Human Plasma by a Sensitive and Robust UPLC-MS-MS Method and Application to a Pharmacokinetic Study in Mexican Subjects. | Patiño-Rodríguez, O., et al. 2015. J Chromatogr Sci. 53: 1373-8. PMID: 25862744
- Pinaverium Bromide: Development and Validation of Spectrophotometric Methods for Assay and Dissolution Studies. | Martins, DDFC., et al. 2017. J AOAC Int. 100: 1747-1753. PMID: 28776492
- Action of pinaverium bromide on calmodulin-regulated functions. | Wuytack, F., et al. 1985. Eur J Pharmacol. 114: 85-8. PMID: 2995077
- Pinaverium Bromide Attenuates Lipopolysaccharide-Induced Excessive Systemic Inflammation via Inhibiting Neutrophil Priming. | Chen, X., et al. 2021. J Immunol. 206: 1858-1865. PMID: 33771933
- Antispasmodics for Chronic Abdominal Pain: Analysis of North American Treatment Options. | Brenner, DM. and Lacy, BE. 2021. Am J Gastroenterol. 116: 1587-1600. PMID: 33993133
- Efficacy of pinaverium bromide in the treatment of irritable bowel syndrome: a systematic review and meta-analysis. | Bor, S., et al. 2021. Therap Adv Gastroenterol. 14: 17562848211033740. PMID: 34539813
- Effect of probiotics and dietary fiber combined with pinaverium bromide on intestinal flora in patients with irritable bowel syndrome. | Sun, H., et al. 2021. Am J Transl Res. 13: 14039-14045. PMID: 35035746
- In Vitro Inhibition of Growth, Biofilm Formation, and Persisters of Staphylococcus aureus by Pinaverium Bromide. | Mao, T., et al. 2023. ACS Omega. 8: 9652-9661. PMID: 36936302
- Effects of pinaverium bromide and verapamil on the motility of the rat isolated colon. | Baumgartner, A., et al. 1985. Br J Pharmacol. 86: 89-94. PMID: 4052731
- Comparison of pinaverium bromide, manganese chloride and D600 effects on electrical and mechanical activities in rat uterine smooth muscle. | Mironneau, J., et al. 1984. Eur J Pharmacol. 98: 99-107. PMID: 6325214
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pinaverium Bromide, 10 mg | sc-219622 | 10 mg | $270.00 | |||
Pinaverium Bromide, 100 mg | sc-219622A | 100 mg | $1022.00 |