Date published: 2025-10-27

1-800-457-3801

SCBT Portrait Logo
Seach Input

Pimelic acid (CAS 111-16-0)

0.0(0)
Write a reviewAsk a question

CAS Number:
111-16-0
Molecular Weight:
160.17
Molecular Formula:
C7H12O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Pimelic acid, an aliphatic dicarboxylic acid, finds applications in the synthesis of polymers and various compounds. It plays a role in the production of polyurethanes, polyesters, and polyamides, making it a component in materials science. Moreover, pimelic acid is utilized in surfactant and solvent synthesis.


Pimelic acid (CAS 111-16-0) References

  1. X-ray studies on crystalline complexes involving amino acids and peptides. XLI. Commonalities in aggregation and conformation revealed by the crystal structures of the pimelic acid complexes of L-arginine and DL-lysine.  |  Saraswathi, NT., et al. 2003. Acta Crystallogr B. 59: 641-6. PMID: 14586085
  2. Biotin synthesis begins by hijacking the fatty acid synthetic pathway.  |  Lin, S., et al. 2010. Nat Chem Biol. 6: 682-8. PMID: 20693992
  3. UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model.  |  Manna, SK., et al. 2011. J Proteome Res. 10: 4120-33. PMID: 21749142
  4. Lipid profiling of the Arabidopsis hypersensitive response reveals specific lipid peroxidation and fragmentation processes: biogenesis of pimelic and azelaic acid.  |  Zoeller, M., et al. 2012. Plant Physiol. 160: 365-78. PMID: 22822212
  5. Pimelic acid, the first precursor of the Bacillus subtilis biotin synthesis pathway, exists as the free acid and is assembled by fatty acid synthesis.  |  Manandhar, M. and Cronan, JE. 2017. Mol Microbiol. 104: 595-607. PMID: 28196402
  6. Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters.  |  Wang, M., et al. 2017. Nat Chem Biol. 13: 660-667. PMID: 28414710
  7. In Vivo Roles of Fatty Acid Biosynthesis Enzymes in Biosynthesis of Biotin and α-Lipoic Acid in Corynebacterium glutamicum.  |  Ikeda, M., et al. 2017. Appl Environ Microbiol. 83: PMID: 28754705
  8. Adaptive laboratory evolution of tolerance to dicarboxylic acids in Saccharomyces cerevisiae.  |  Pereira, R., et al. 2019. Metab Eng. 56: 130-141. PMID: 31550508
  9. Formation of a biotin precursor, pimelic acid, in yeasts from C18 fatty acids.  |  Ohsugi, M., et al. 1988. J Nutr Sci Vitaminol (Tokyo). 34: 343-52. PMID: 3236079
  10. Bisthioureas of pimelic acid and 4-methylsalicylic acid derivatives as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP) and intestinal alkaline phosphatase (IAP): Synthesis and molecular docking studies.  |  Mumtaz, A., et al. 2020. Bioorg Chem. 101: 103996. PMID: 32563965
  11. Use of additives to regulate solute aggregation and direct conformational polymorph nucleation of pimelic acid.  |  Shi, P., et al. 2021. IUCrJ. 8: 161-167. PMID: 33708393
  12. The Friction of Structurally Modified Isotactic Polypropylene.  |  Wierzbicka, N., et al. 2021. Materials (Basel). 14: PMID: 34885617
  13. Claisen Condensation Reaction Mediated Pimelate Biosynthesis via the Reverse Adipate-Degradation Pathway and Its Isoenzymes.  |  Bao, Q., et al. 2022. Chembiochem. 23: e202200098. PMID: 35352865
  14. Formation of Salts and Molecular Ionic Cocrystals of Fluoroquinolones and α,ω-Dicarboxylic Acids.  |  O'Malley, C., et al. 2022. Cryst Growth Des. 22: 3060-3071. PMID: 35529070
  15. Pattern of aliphatic dicarboxylic acids in uremic serum including a new organic acid, 2,4-dimethyladipic acid.  |  Niwa, T., et al. 1979. Clin Chim Acta. 99: 71-83. PMID: 498544

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pimelic acid, 25 g

sc-258017
25 g
$42.00