Pimecrolimus CAS: 137071-32-0
MF: C43H68ClNO11
MW: 810.45
An immunosuppressant asomycin derivative.
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Pimecrolimus (CAS 137071-32-0)

Pimecrolimus | CAS 137071-32-0 is rated 5.0 out of 5 by 1.
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Alternate Names: 33-Epichloro-33-desoxyascomycin; Elidel
Application: Pimecrolimus is an immunosuppressant asomycin derivative
CAS Number: 137071-32-0
Molecular Weight: 810.45
Molecular Formula: C43H68ClNO11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

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A macrolactam ascomycin derivative which inhibits production of pro-inflammatory cytokines by T cells and mast cells.


References

Gassberger, M., et al.: Br. J. Dermatol., 141, 264 (1999), Queille-Roussel, C., et al.: Contact Dermatitis, 42, 349 (2000),

Physical State :
Solid
Storage :
Store at 4° C
Melting Point :
142-144° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6447131
SMILES :
CC[[email protected]@H]1\\C=C(C)\\C[[email protected]](C)C[[email protected]](OC)[[email protected]]2O[[email protected]](O)([[email protected]](C)C[[email protected]@H]2OC)C(=O)C(=O)N2CCCC[[email protected]]2C(=O)O[[email protected]@H]([[email protected]](C)[[email protected]@H](O)CC1=O)C(\\C)=C\\[[email protected]@H]1CC[[email protected]](Cl)[[email protected]@H](C1)OC

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Certificate of Analysis

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Pimecrolimus (CAS 137071-32-0)  Product Citations

See how others have used Pimecrolimus (CAS 137071-32-0). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 28400912  Xu, S.|Li, L.|Li, M.|Zhang, M.|Ju, M.|Chen, X.|Gu, H.| et al. 2017. Oxid Med Cell Longev. 2017: 5930639.

PMID: # 30883607  PLoS Pathog. e1007601.

Citations 1 to 2 of 2 total
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Rated 5 out of 5 by from Yoon Yoon, NY. et al. (PubMed 25786383) reported that topical glucocorticoid or Pimecrolimus treatment suppressed thymic stromal lymphopoietin-related allergic inflammatory mechanism in an oxazolone-induced atopic dermatitis murine model. -SCBT Publication Review
Date published: 2015-07-09
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