Date published: 2026-4-29

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Pigment Red 254 (CAS 84632-65-5)

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Alternate Names:
3,6-Bis(4-chlorophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione
CAS Number:
84632-65-5
Molecular Weight:
357.19
Molecular Formula:
C18H10Cl2N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pigment Red 254 (PR254) represents a synthetic dye that has found diverse applications, spanning from cosmetics to medical treatments. This dye belongs to the azo dye family, characterized by compounds containing a double bond linking two nitrogen atoms. Pigment Red 254′s broad range of applications stems from its unique properties, particularly its capacity to absorb light within the visible spectrum. In the realm of scientific research, Pigment Red 254 enjoys extensive usage. It serves as a fluorescent dye for cell and tissue imaging, leveraging its ability to absorb visible light and emit light within the near-infrared spectrum. Consequently, it proves ideal for visualizing deep tissue structures. Moreover, Pigment Red 254 has played a role in DNA sequencing and protein sequencing applications. By binding to specific molecules and fluorescing, it enables researchers to track and quantify these molecules. The precise mechanism of action underlying Pigment Red 254 remains partially elusive. It is hypothesized that the dye binds to various cellular molecules such as proteins and DNA, subsequently emitting light upon exposure to visible light. This mechanism enables its use in imaging and other related applications.


Pigment Red 254 (CAS 84632-65-5) References

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  2. Towards AOP application--implementation of an integrated approach to testing and assessment (IATA) into a pipeline tool for skin sensitization.  |  Patlewicz, G., et al. 2014. Regul Toxicol Pharmacol. 69: 529-45. PMID: 24928565
  3. Unintentional PCB in chlorophenylsilanes as a source of contamination in environmental samples.  |  Anezaki, K. and Nakano, T. 2015. J Hazard Mater. 287: 111-7. PMID: 25634145
  4. Hydrogen-bonded diketopyrrolopyrrole (DPP) pigments as organic semiconductors.  |  Głowacki, ED., et al. 2014. Org Electron. 15: 3521-3528. PMID: 25642158
  5. Thermal decomposition of nano-enabled thermoplastics: Possible environmental health and safety implications.  |  Sotiriou, GA., et al. 2016. J Hazard Mater. 305: 87-95. PMID: 26642449
  6. Comparative short-term inhalation toxicity of five organic diketopyrrolopyrrole pigments and two inorganic iron-oxide-based pigments.  |  Hofmann, T., et al. 2016. Inhal Toxicol. 28: 463-79. PMID: 27387137
  7. Nanofiller Presence Enhances Polycyclic Aromatic Hydrocarbon (PAH) Profile on Nanoparticles Released during Thermal Decomposition of Nano-enabled Thermoplastics: Potential Environmental Health Implications.  |  Singh, D., et al. 2017. Environ Sci Technol. 51: 5222-5232. PMID: 28397486
  8. Environmental Impacts by Fragments Released from Nanoenabled Products: A Multiassay, Multimaterial Exploration by the SUN Approach.  |  Amorim, MJB., et al. 2018. Environ Sci Technol. 52: 1514-1524. PMID: 29376638
  9. Mass Spectrometric Analysis of Synthetic Organic Pigments.  |  Sugaya, N., et al. 2018. J AOAC Int. 101: 1328-1340. PMID: 29669623
  10. Micropigmentation for vitiligo on light to moderately colored skin: Updated evidence from a clinical and animal study.  |  Ju, HJ., et al. 2020. J Dermatol. 47: 464-469. PMID: 32124487
  11. Assessment of cytotoxicity and sensitization potential of intradermally injected tattoo inks in reconstructed human skin.  |  Karregat, JJJP., et al. 2021. Contact Dermatitis. 85: 324-339. PMID: 34029376
  12. A Convenient Synthesis of Diketopyrrolopyrrole Dyes.  |  Almodôvar, VAS. and Tomé, AC. 2021. Molecules. 26: PMID: 34443350
  13. The improvement in hole-transporting and electroluminescent properties of diketopyrrolopyrrole pigment by grafting with carbazole dendrons.  |  Kitisriworaphan, W., et al. 2021. RSC Adv. 11: 12710-12719. PMID: 35423806

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pigment Red 254, 25 g

sc-473757
25 g
$147.00