Date published: 2026-4-19

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Pigment Red 22 (CAS 6448-95-9)

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Alternate Names:
3-Hydroxy-4-((5-nitro-o-tolyl)azo)-2-naphthanilide
CAS Number:
6448-95-9
Molecular Weight:
426.42
Molecular Formula:
C24H18N4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pigment Red 22 is used in increasing the solubility of industrial azo pigments for NMR spectra and the determination of NMR peak assignments. It has been used in a variety of scientific research applications, including exploring the impact of ultraviolet radiation on the skin and investigating the consequences of oxidative stress on cellular systems. Pigment Red 22 exhibits an absorption maximum around 613 nm and demonstrates favorable water solubility.


Pigment Red 22 (CAS 6448-95-9) References

  1. Photochemical cleavage of a tattoo pigment by UVB radiation or natural sunlight.  |  Engel, E., et al. 2007. J Dtsch Dermatol Ges. 5: 583-9. PMID: 17610608
  2. Modern tattoos cause high concentrations of hazardous pigments in skin.  |  Engel, E., et al. 2008. Contact Dermatitis. 58: 228-33. PMID: 18353031
  3. Tattooing of skin results in transportation and light-induced decomposition of tattoo pigments--a first quantification in vivo using a mouse model.  |  Engel, E., et al. 2010. Exp Dermatol. 19: 54-60. PMID: 19703227
  4. The decrease of pigment concentration in red tattooed skin years after tattooing.  |  Lehner, K., et al. 2011. J Eur Acad Dermatol Venereol. 25: 1340-5. PMID: 21349116
  5. Identification and differentiation of the red ink entries of seals on document by laser desorption ionization mass spectrometry.  |  Wang, XF., et al. 2014. Forensic Sci Int. 236: 99-108. PMID: 24529780
  6. Azo pigments and quinacridones induce delayed hypersensitivity in red tattoos.  |  Gaudron, S., et al. 2015. Contact Dermatitis. 72: 97-105. PMID: 25441375
  7. Patterns of Reactions to Red Pigment Tattoo and Treatment Methods.  |  Forbat, E. and Al-Niaimi, F. 2016. Dermatol Ther (Heidelb). 6: 13-23. PMID: 26972808
  8. A method for increasing the solubility of industrial azo pigments for 13 C and 1 H NMR spectra and the assignments of their 13 C and 1 H NMR peaks.  |  Zhu, M., et al. 2021. Magn Reson Chem. 59: 804-814. PMID: 33559222
  9. Analytical survey of tattoo inks-A chemical and legal perspective with focus on sensitizing substances.  |  Wang, X., et al. 2021. Contact Dermatitis. 85: 340-353. PMID: 34089526
  10. Tattoo Pigment Biokinetics in vivo in a 28-Day Porcine Model: Elements Undergo Fast Distribution to Lymph Nodes and Reach Steady State after 7 Days.  |  Cambiaso-Daniel, J., et al. 2024. Dermatology. 240: 304-311. PMID: 38402858

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pigment Red 22, 1 g

sc-491868
1 g
$233.00