Date published: 2025-12-29

1-800-457-3801

SCBT Portrait Logo
Seach Input

Picrolonic acid (CAS 550-74-3)

0.0(0)
Write a reviewAsk a question

Alternate Names:
3-Methyl-4-nitro-1-(4-nitrophenyl)-5-pyrazolone
Application:
Picrolonic acid is used in the analysis of alkaloids, Ca2+ determination, and the isolation of amines
CAS Number:
550-74-3
Purity:
≥98%
Molecular Weight:
264.20
Molecular Formula:
C10H8N4O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Picrolonic acid is a distinctive organic compound recognized for its role as a potent nitrating agent, integral to various synthetic organic chemistry applications. Structurally characterized by a nitrated phenol group, picrolonic acid facilitates the transfer of nitro groups to other organic molecules, a process central to altering their chemical properties. This capability makes it particularly useful in research for studying the kinetics and mechanisms of nitration reactions, providing insights into how electronic effects influence the reactivity of aromatic ring systems. In practical applications, picrolonic acid is employed in the synthesis of dyes, explosives, and pharmaceutical intermediates, where its selective nitration is crucial for achieving desired molecular structures. Additionally, its use extends to the development of new synthetic methodologies, significantly enhancing the efficiency and specificity of nitration processes. Through these applications, picrolonic acid not only acts as a valuable chemical reagent but also contributes to advancing the field of organic synthesis, by enabling more controlled and precise chemical transformations.


Picrolonic acid (CAS 550-74-3) References

  1. Picrolonic acid: a novel frameshift mutagen.  |  Rosenkranz, HS. and Stein, AB. 1975. Mutat Res. 28: 127-9. PMID: 1095916
  2. Spectrophotometric analysis of alkaloids with picrolonic acid.  |  Taha, AM. and Gomaa, CS. 1976. J Assoc Off Anal Chem. 59: 683-8. PMID: 1270400
  3. [UV spectrophotometric assay of famotidine in combination with picrolonic acid, picrolinate].  |  Apostu, M., et al. 2005. Rev Med Chir Soc Med Nat Iasi. 109: 422-5. PMID: 16607813
  4. Comparative Responses of Globodera rostochiensis and G. pallida to Hatching Chemicals.  |  Byrne, JT., et al. 2001. J Nematol. 33: 195-202. PMID: 19265881
  5. [Study of the response characteristics of PVC membrane ion-associate type electrodes for organic base cations].  |  Kang, XJ. and Wang, CY. 1990. Yao Xue Xue Bao. 25: 904-9. PMID: 2104469
  6. Antimutagenic properties of Mangifera indica L. stem bark extract and evaluation of its effects on hepatic CYP1A1.  |  Morffi, J., et al. 2012. Plant Foods Hum Nutr. 67: 223-8. PMID: 22865094
  7. Antimutagenic activity of extracts from anticancer drugs in Chinese medicine.  |  Lee, H. and Lin, JY. 1988. Mutat Res. 204: 229-34. PMID: 3278214
  8. Synergistic Extraction of Europium (III) using Di-n-Butylsulfoxide and Picrolonic Acid.  |  Fazil, S., et al. 2022. Comb Chem High Throughput Screen. 25: 861-869. PMID: 33568027
  9. Picrolonic acid as a hatching agent for the potato cyst nematode, Heterodera rostochiensis Woll.  |  Clarke, AJ. and Shepherd, AM. 1966. Nature. 211: 546. PMID: 6007775

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Picrolonic acid, 1 g

sc-296088
1 g
$127.00

Picrolonic acid, 2.5 g

sc-296088A
2.5 g
$209.00

Picrolonic acid, 10 g

sc-296088B
10 g
$770.00

Picrolonic acid, 50 g

sc-296088C
50 g
$1433.00