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PI 3-kinase C2β Antibody (22) is a mouse monoclonal IgG1 antibody that detects PI 3-kinase C2β in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). PI 3-kinase C2β, also known as p110-β, is a crucial 1,070 amino acid protein that plays a significant role in cellular signaling pathways, particularly those that regulate cell growth and survival in response to various mitogenic stimuli. Anti-PI 3-kinase C2β antibody (22) recognizes a protein primarily located in the cytoplasm and involved in the modulation of integrin adhesion bonds, specifically α2B (ITGA2B) and β3 (ITGB3), which are vital for platelet activation under shear stress conditions. The interaction between PI 3-kinase C2β and these integrins is essential for maintaining proper hemostasis and responding to vascular injury, highlighting PI 3-kinase C2β′s importance in both normal physiology and pathological conditions such as thrombosis. With participation in critical signaling pathways, PI 3-kinase C2β serves as a valuable target for research into cell growth regulation and related diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PI 3-kinase C2β Antibody (22) | sc-136031 | 50 µg/0.5 ml | $322.00 |