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Phytic acid dipotassium salt (CAS 129832-03-7)

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Alternate Names:
Phytic acid dipotassium salt is also known as Inositol hexakisphosphate.
Application:
Phytic acid dipotassium salt is a potent chelator of divalent and trivalent cations, and a major determinant of zinc bioavailability.
CAS Number:
129832-03-7
Purity:
≥95%
Molecular Weight:
736.22
Molecular Formula:
C6H16O24P62K
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Phytic acid dipotassium salt is present in all eukaryotic cells. In plants, Phytic acid dipotassium salt functions as a [PO4]3- storage depot and precursor for other inositol phosphates and pyrophosphates. The high surface negative charge of makes Phytic acid dipotassium salt a potent chelator of divalent and trivalent cations in vitro. Phytic acid dipotassium salt is most likely associated with Ca2+ or Mg2+ ions in vivo. In yeast, Phytic acid dipotassium salt acts with the nuclear pore protein Gle1 to regulate the nuclear export of mRNA by coactivating the RNA-dependent ATPase activity of DExD-box protein 5 (Dbp5).


Phytic acid dipotassium salt (CAS 129832-03-7) References

  1. Speciation of phytate ion in aqueous solution. Alkali metal complex formation in different ionic media.  |  De Stefano, C., et al. 2003. Anal Bioanal Chem. 376: 1030-40. PMID: 12856098
  2. Optimization of the treatment of wheat samples for the determination of phytic acid by HPLC with refractive index detection.  |  Amaro, R., et al. 2009. J AOAC Int. 92: 873-8. PMID: 19610380
  3. Phytate reduction in bran-enriched bread by phytase-producing bifidobacteria.  |  Sanz-Penella, JM., et al. 2009. J Agric Food Chem. 57: 10239-44. PMID: 19817458
  4. Phytase activity from Lactobacillus spp. in calcium-fortified soymilk.  |  Tang, AL., et al. 2010. J Food Sci. 75: M373-6. PMID: 20722939
  5. Identification of myo-inositol hexakisphosphate (IP6) as a β-secretase 1 (BACE1) inhibitory molecule in rice grain extract and digest.  |  Abe, TK. and Taniguchi, M. 2014. FEBS Open Bio. 4: 162-7. PMID: 24649396
  6. Efficacy of Mixtures of Magnesium, Citrate and Phytate as Calcium Oxalate Crystallization Inhibitors in Urine.  |  Grases, F., et al. 2015. J Urol. 194: 812-9. PMID: 25818031
  7. Expression of bifidobacterial phytases in Lactobacillus casei and their application in a food model of whole-grain sourdough bread.  |  García-Mantrana, I., et al. 2016. Int J Food Microbiol. 216: 18-24. PMID: 26384212
  8. Dietary Strategies To Reduce the Bioaccessibility of Arsenic from Food Matrices.  |  Clemente, MJ., et al. 2016. J Agric Food Chem. 64: 923-31. PMID: 26766512
  9. The RNA export factor Mex67 functions as a mobile nucleoporin.  |  Derrer, CP., et al. 2019. J Cell Biol. 218: 3967-3976. PMID: 31753862
  10. Isolation and identification of lactic acid bacteria with phytase activity from sourdough.  |  Mohammadi-Kouchesfahani, M., et al. 2019. Food Sci Nutr. 7: 3700-3708. PMID: 31763019
  11. Enhanced Energy Density for P-Doped Hierarchically Porous Carbon-Based Symmetric Supercapacitor with High Operation Potential in Aqueous H2SO4 Electrolyte.  |  Wu, X., et al. 2021. Nanomaterials (Basel). 11: PMID: 34835603
  12. Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.  |  Acquistapace, IM., et al. 2022. Int J Mol Sci. 23: PMID: 35683026
  13. Determination of phytic acid and its degradation products by ion-pair chromatography (IPC) coupled to inductively coupled plasma-sector field-mass spectrometry (ICP-SF-MS)  |  A Helfrich, J Bettmer. 2004. Journal of Analytical Atomic Spectrometry. 19: 1330-1334.
  14. Equilibrium, thermoanalytical and spectroscopic studies to characterize phytic acid complexes with Mn (II) and Co (II)  |  LD Carli, E Schnitzler, M Ionashiro. 2009. Journal of the Brazilian. 20: 1515-1522.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phytic acid dipotassium salt, 5 g

sc-253276
5 g
$229.00

Phytic acid dipotassium salt, 25 g

sc-253276A
25 g
$473.00

Hello, First, I would like to ask how this phytate is synthesized, chemically or biologically. And second, how is the purity of this tested? Commercial phytate is often contaminated with lower order isomers and phytase enzymes. Thank you.

Asked by: Tonyh
Thank you for your question. It would be helpful if you could call 800-457-3801, allowing for a more interactive discussion of this and other related questions.
Answered by: Technical Service
Date published: 2023-03-13
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Rated 5 out of 5 by from FuFu, et al. (PubMed ID 26385515) reported that phytic acid (IP6) modulates the TJ proteins' localization and down regulates expression of TJ proteins (including claudin-1, occludin and ZO-1), leading to a loss in integrity of Caco-2 cell monolayers. -SCBT Publication Review
Date published: 2015-06-07
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Phytic acid dipotassium salt is rated 5.0 out of 5 by 1.
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