Date published: 2025-11-3

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Photobiotin acetate salt (CAS 96087-38-6)

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Alternate Names:
Biotin {3-[3-(4-azido-2-nitroanilino)-N-methylpropylamino]propylamide} acetate salt
Application:
Photobiotin acetate salt is A photo-activatable biotin analogue
CAS Number:
96087-38-6
Purity:
≥95%
Molecular Weight:
593.70
Molecular Formula:
C23H35N9O4S•C2H4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Photobiotin acetate salt is a photo-activatable biotin analogue used for the reproducible and scalable preparation of stable DNA and RNA probes. Nucleic acid probes prepared with photobiotin will detect as little as 0.5 pg of target DNA. Upon brief irradiation with light, photobiotin labels single or double stranded nucleic acids. The mechanism of action of photobiotin acetate relies on its unique capability to selectively bind to specific proteins and enzymes. Through its biotin moiety, photobiotin acetate forms interactions with biotin-binding proteins, while its acetate moiety engages with other proteins and enzymes. This binding phenomenon enables photobiotin acetate to function as a substrate or cofactor in biochemical reactions.


Photobiotin acetate salt (CAS 96087-38-6) References

  1. Preparation, characterization and biological properties of biotinylated derivatives of calmodulin.  |  Polli, JW. and Billingsley, ML. 1991. Biochem J. 275 (Pt 3): 733-43. PMID: 1645521
  2. Photobiotin-labeled DNA and RNA hybridization probes.  |  McInnes, JL., et al. 1988. Methods Mol Biol. 4: 401-14. PMID: 21424650
  3. Bacillus thaonhiensis sp. nov., a new species, was isolated from the forest soil of Kyonggi University by using a modified culture method.  |  Van Pham, HT. and Kim, J. 2014. Curr Microbiol. 68: 88-95. PMID: 23995763
  4. Degree of biotinylation in nucleic acids estimated by a gel retardation assay.  |  Theissen, G., et al. 1989. Anal Biochem. 179: 98-105. PMID: 2474260
  5. Non-radioactive hybridization probes prepared by the chemical labelling of DNA and RNA with a novel reagent, photobiotin.  |  Forster, AC., et al. 1985. Nucleic Acids Res. 13: 745-61. PMID: 2582358
  6. Detection of flavivirus RNA in infected cells using photobiotin-labelled hybridization probes.  |  Khan, AM. and Wright, PJ. 1987. J Virol Methods. 15: 121-30. PMID: 3031110
  7. Suppression of postischemic hippocampal nerve growth factor expression by a c-fos antisense oligodeoxynucleotide.  |  Cui, JK., et al. 1999. J Neurosci. 19: 1335-44. PMID: 9952411
  8. Microfluidic devices with integrated dual-capacitively coupled contactless conductivity detection to monitor binding events in real time  |  WKT Coltro, R de Santis Neves. 2014. Elsevier Sensors and Actuators B: Chemical. 192: 239-246.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Photobiotin acetate salt, 1 mg

sc-215717
1 mg
$559.00

Photobiotin acetate salt, 2 mg

sc-215717A
2 mg
$938.00