Date published: 2025-12-19

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Phosphomolybdic acid (CAS 51429-74-4)

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Alternate Names:
Molydophosphoric acid; 12-Molybdophosphoric acid
Application:
Phosphomolybdic acid is a reagent used for spectrophotometric determination of phosphate ions
CAS Number:
51429-74-4
Molecular Weight:
1825.25
Molecular Formula:
H3PO412MoO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Phosphomolybdic acid (PMA) hydrate is primarily used in spectrophotometric determination of phosphate ions. PMA is a component in the 3-color histology stain called Masson's trichrome; employed in the differentiation step, Phosphomolybdic acid is one of the solutions fixed tissues are immersed in prior to subsequent staining. Phosphomolybdic acid is also used as reagent for simple and rapid colorimetric determination of phenothiazine derivatives. PMA oxidizes the phenothiazine derivative to a cationic free radical, forming a coloured salt. A preliminary extraction is necessary if certain reductants (sulphite or ascorbic acid) are present as stabilizers, as they will reduce the reagent to phosphomolybdenum blue.
Also available in solution: Phosphomolybdic acid solution (sc-203346)


Phosphomolybdic acid (CAS 51429-74-4) References

  1. The organic solvent effect on phosphomolybdic acid and its analytical application.  |  Fujinaga, T., et al. 1971. Talanta. 18: 960-2. PMID: 18960967
  2. Phosphomolybdic acid as a reagent for the spectrophotometric determination of certain phenothiazine derivatives of pharmaceutical products.  |  Stan, M., et al. 1977. Talanta. 24: 140-2. PMID: 18962047
  3. Facile ring-opening of oxiranes by H(2)O(2) catalyzed by phosphomolybdic acid.  |  Li, Y., et al. 2009. Org Lett. 11: 2691-4. PMID: 19514796
  4. Phosphomolybdic acid immobilized on graphite as an environmental photoelectrocatalyst.  |  Aber, S., et al. 2016. Chemosphere. 161: 422-428. PMID: 27448755
  5. Phosphomolybdic acid supported single-metal-atom catalysis in CO oxidation: first-principles calculations.  |  Yu, MA., et al. 2018. Phys Chem Chem Phys. 20: 20661-20668. PMID: 30059111
  6. Phosphomolybdic Acid Prevents Nonspecific Nuclear Staining by Picrosirius Red but Is Converted to Molybdenum Blue by Blue Light.  |  Hatori, M., et al. 2020. J Histochem Cytochem. 68: 621-634. PMID: 32674674
  7. Phosphomolybdic Acid-Modified Monolayer Graphene Anode for Efficient Organic and Perovskite Light-Emitting Diodes.  |  Liu, L., et al. 2021. ACS Appl Mater Interfaces. 13: 12268-12277. PMID: 33656843
  8. Brønsted Acid-Catalyzed Carbonyl-Olefin Metathesis: Synthesis of Phenanthrenes via Phosphomolybdic Acid as a Catalyst.  |  Chen, Y., et al. 2022. J Org Chem. 87: 351-362. PMID: 34928599
  9. Phosphomolybdic acid enhancing hexavalent chromium bio-reduction in long-term operation: Optimal dosage and mechanism analysis.  |  Wu, Y., et al. 2024. Sci Total Environ. 906: 167328. PMID: 37751836
  10. Introducing VO2+ Group in Phosphomolybdic Acid and Supporting on MOF-808 for Efficient Oxidative Desulfurization.  |  Ping, Y., et al. 2023. ACS Omega. 8: 37421-37430. PMID: 37841163

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phosphomolybdic acid, 25 g

sc-215711
25 g
$65.00

Phosphomolybdic acid, 100 g

sc-215711A
100 g
$123.00