Date published: 2025-10-12

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Phosphodiesterase 4 Inhibitor (CAS 346440-86-6)

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Application:
Phosphodiesterase 4 Inhibitor is a pyrazole compound with an active site binding inhibitor of phosphodiester
CAS Number:
346440-86-6
Purity:
≥97%
Molecular Weight:
289.3
Molecular Formula:
C14H15N3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pyrazole compound with a high-affinity active site binding inhibitor of phosphodiesterases IVB and IVD (IC50 = 33 nM and 21 nM). More potent than Rolipram (IC50 = 570 nM and 1.1 µM for PDEIVB and PDEIVD), respectively and greater selectivity over PDEIB, PDEIIA, PDEIIIB, PDEVA, PDEVIIB, PDEVIIIA, PDEIXA and PDEXIA (IC50 > 30 µM) and minimally inhibit PDEXA with an IC50 of 6.9 µM.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phosphodiesterase 4 Inhibitor, 10 mg

sc-204190
10 mg
$280.00

Phosphodiesterase 4 Inhibitor, 50 mg

sc-204190A
50 mg
$1300.00