Date published: 2025-10-2

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Phosphocreatine (CAS 67-07-2)

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Alternate Names:
Creatine phosphate; Creatinephosphoric acid; N-(Phosphonoamidino)sarcosine
CAS Number:
67-07-2
Purity:
≥92%
Molecular Weight:
211.11
Molecular Formula:
C4H10N3O5P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Phosphocreatine is a high-energy phosphate compound that is present in human cells and serves as a primary energy source for muscle contractions and other cellular functions. This compound is synthesized from the breakdown of creatine, an organic substance that is vital for normal muscle function. Phosphocreatine is involved in the production of adenosine triphosphate (ATP), the primary source of energy for cellular metabolism, and is found in the mitochondria. Due to its role in ATP production, phosphocreatine is frequently used in studies examining muscle metabolism.


Phosphocreatine (CAS 67-07-2) References

  1. Luminometric assays of ATP, phosphocreatine, and creatine for estimation of free ADP and free AMP.  |  Ronner, P., et al. 1999. Anal Biochem. 275: 208-16. PMID: 10552906
  2. Role of creatine and phosphocreatine in neuronal protection from anoxic and ischemic damage.  |  Balestrino, M., et al. 2002. Amino Acids. 23: 221-9. PMID: 12373542
  3. Phosphocreatine as a determinant of K(ATP) channel activity in pancreatic beta-cells.  |  Krippeit-Drews, P., et al. 2003. Pflugers Arch. 445: 556-62. PMID: 12634926
  4. Muscle [phosphocreatine] dynamics during exercise: implication for understanding the regulation of muscle oxidative metabolism.  |  Menuet, C. and Arsac, LM. 2008. J Physiol. 586: 3027-9. PMID: 18483068
  5. The phosphocreatine-creatine kinase system helps to shape muscle cells and keep them healthy and alive.  |  Saks, V. 2008. J Physiol. 586: 2817-8. PMID: 18556720
  6. Bioenergetic consequences of cardiac phosphocreatine depletion induced by creatine analogue feeding.  |  Zweier, JL., et al. 1991. J Biol Chem. 266: 20296-304. PMID: 1939088
  7. Determination of creatine and phosphocreatine in muscle biopsy samples by capillary electrophoresis with contactless conductivity detection.  |  See, HH., et al. 2012. Anal Chim Acta. 727: 78-82. PMID: 22541827
  8. Role of the phosphocreatine system on energetic homeostasis in skeletal and cardiac muscles.  |  Guimarães-Ferreira, L. 2014. Einstein (Sao Paulo). 12: 126-31. PMID: 24728259
  9. Potential of creatine or phosphocreatine supplementation in cerebrovascular disease and in ischemic heart disease.  |  Balestrino, M., et al. 2016. Amino Acids. 48: 1955-67. PMID: 26795537
  10. eComment. Phosphocreatine in cardiovascular disease: how can we relate the evidence to clinical practice?  |  Brown, OI. 2016. Interact Cardiovasc Thorac Surg. 23: 646. PMID: 27672178
  11. Potential possibility of phosphocreatine usage in internal medicine.  |  Vnučák, M., et al. 2019. Vnitr Lek. 65: 30-36. PMID: 30823835
  12. Compartmentation of adenine nucleotides and phosphocreatine shuttle in cardiac cells: some new evidence.  |  Saks, VA., et al. 1986. Adv Exp Med Biol. 194: 103-16. PMID: 3529852
  13. Measurement of phosphocreatine in cutaneous tissue by high pressure liquid chromatography.  |  Zemtsov, A., et al. 1993. Am J Med Sci. 305: 8-11. PMID: 8416683

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phosphocreatine, 2.5 g

sc-477537
2.5 g
$230.00

Phosphocreatine, 25 g

sc-477537A
25 g
$496.00

Phosphocreatine, 100 g

sc-477537B
100 g
$1342.00