Molecular structure of Phosphatidic Acid, Dipalmitoyl, CAS Number: 169051-60-9
Phosphatidic Acid, Dipalmitoyl (CAS 169051-60-9)
Alternate Names:
1,2-Dipalmitoyl-sn-glycero-3-phosphate monosodium salt
Application:
Phosphatidic Acid, Dipalmitoyl is a compound that activates MAPK
CAS Number:
169051-60-9
Purity:
98%
Molecular Weight:
670.87
Molecular Formula:
C35H68O8P•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Phosphatidic Acid, Dipalmitoyl is produced by phospholipase D through the hydrolysis of phosphatidylcholine. The compound has been reported to activate the mitogen-activated protein kinase (MAPK) cascade, and interacts with Raf-1 by binding and mediating its translocation to the plasma membrane. Studies show that Phosphatidic Acid is an intracellular pH biosensor and couples metabolism to membrane biogenesis.
Phosphatidic Acid, Dipalmitoyl (CAS 169051-60-9) References
- The recruitment of Raf-1 to membranes is mediated by direct interaction with phosphatidic acid and is independent of association with Ras. | Rizzo, MA., et al. 2000. J Biol Chem. 275: 23911-8. PMID: 10801816
- Combined radiofrequency ablation and adjuvant liposomal chemotherapy: effect of chemotherapeutic agent, nanoparticle size, and circulation time. | Ahmed, M., et al. 2005. J Vasc Interv Radiol. 16: 1365-71. PMID: 16221908
- From specular reflectivity to time-resolved grazing incidence X-ray scattering out of the specular plane (GISAXS): equilibrium and nonequilibrium states of organic/inorganic monolayers at liquid surfaces. | Wiegart, L., et al. 2009. Langmuir. 25: 4104-10. PMID: 19714894
- Synthesis of dehydroepiandrosterone analogues modified with phosphatidic acid moiety. | Smuga, DA., et al. 2010. Steroids. 75: 1146-52. PMID: 20727366
- Phosphatidic acid is a pH biosensor that links membrane biogenesis to metabolism. | Young, BP., et al. 2010. Science. 329: 1085-8. PMID: 20798321
- Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice. | Wellner, N., et al. 2011. Biochim Biophys Acta. 1811: 508-12. PMID: 21723414
- Evaluation and optimization of high-performance liquid chromatography coupled with high-resolution mass spectrometry for phospholipid quantitation. | Fu, M., et al. 2014. Rapid Commun Mass Spectrom. 28: 811-21. PMID: 24573813
- Design and Characterization of Fibrin-Based Acoustically Responsive Scaffolds for Tissue Engineering Applications. | Moncion, A., et al. 2016. Ultrasound Med Biol. 42: 257-71. PMID: 26526782
- Development and in vitro evaluation of zeta potential changing self-emulsifying drug delivery systems for enhanced mucus permeation. | Suchaoin, W., et al. 2016. Int J Pharm. 510: 255-62. PMID: 27329673
- Diagnosis of prostate cancer using anti-PSMA aptamer A10-3.2-oriented lipid nanobubbles. | Fan, X., et al. 2016. Int J Nanomedicine. 11: 3939-50. PMID: 27574424
- Nonideal mixing and phase separation in phosphatidylcholine-phosphatidic acid mixtures as a function of acyl chain length and pH. | Garidel, P., et al. 1997. Biophys J. 72: 2196-210. PMID: 9129822
- Phospholipase D and its product, phosphatidic acid, mediate agonist-dependent raf-1 translocation to the plasma membrane and the activation of the mitogen-activated protein kinase pathway. | Rizzo, MA., et al. 1999. J Biol Chem. 274: 1131-9. PMID: 9873061
- Design and Synthesis of Phosphatidylcholine Mimics and Their Mixing Behavior with Phosphatidylglycerol Mimics in the Fluid Bilayer State | Maki Uragami, Yasuhito Miyake, Nobuya Tokutake, Lan-hui Zhang, and Steven L. Regen. 2000. Langmuir. 16, 21: 8010–8015.
Inhibitor of:
ZSCAN12.Activator of:
1810030N24Rik, 2010001M09Rik, 2310033E01Rik, 3BP1, 4933425O20Rik, 4933427G17Rik, 6330407J23Rik, 6330503C03Rik, 9130011J15Rik, 9230110F15Rik, 9230113P08Rik, 9330101J02Rik, 9930021D14Rik, ARRDC5, Bcl-7a, Cd59b, COL4A4, CPSF4L, CRISP-11, Desmuslin, DGAT1, DGAT2, DSCR 5, FAM160A1, FAM193A, FAPP2, FBF1, FGF-22, FK-506, FLJ23152, FLJ32549, FLJ40142, FLJ46838, FMVB12B, FRMD1, FRMPD2L2, G7c, Gastrokine 1, GDE4, GDPD3, GFOD1, GLIPR1L1, GLT1D1, GLTPD2, GMD, golgin 45, GPN3, group V PLA2, HCFC1R1, HEBP2, HS1BP3, IMPA1, JAKMIP3, KIAA1109, LAR, LCE1, LCE45A, LOC100131831, LOC100132247, LOC100132396, LOC100132413, LOC643278, LPAAT-β, Ly49I, Ly6G5c, LYG2, LYRM2, MEK-5, Myeov, Myosin IXb, Myotilin, NPAL1, Olr1111, Olr1433, Olr1462, Olr1472, Olr1488, Olr150, Olr1513, ORP-8, OTTMUSG00000005737, OTTMUSG00000005931, PAcP, PAP21, PDC-TREM, Pet2, PI 4-kinase α, Pi15, PIG-preY, Pilr-β2, Pilt, Pira1, Pira2, Pira4, PLP-A, PLP-Cα, PLP-Cγ, PLP-E, PLP-H, PP11, PPIL6, PPP1R6, PQLC3, PRB2, PRB4, Profilin-4, PSD4, PTPγ, Rab 44, Raptor, RBMS2, Rhox8, RHOXF2B, Ribosomal Protein S15a, Ribosomal Protein S25, RILPL2, RIMKLB, Ripply2, RNF103, RP11-307F22.3, Rshl2b, RSPH9, SBEM, SFRS17B, SFT2D1, SFTPG, Shank2, Silg111, StARD13, TBC1D22B, TMEM221, Trav12d-3, Trav12n-2, Trav13d-4, Trav14n-1, Trav16d, Trav4d-3, Trav4n-4, Trav6d-3, TRIM77, Tsga8, TSP50, TSPY3, TSSK 5, TTC30A2, TTP-L, Ubie, UNQ464, UPLP, UTP6, V1rc3132, V1RI10, V1RI3, V1RI5, Vgl-2, VPS13C, WFDC6A, WINS2, Xlr3b, Xlr4a, Xlr5a, Xlr5c, and Xmr.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Phosphatidic Acid, Dipalmitoyl, 100 mg | sc-201057 | 100 mg | $104.00 | |||
Phosphatidic Acid, Dipalmitoyl, 250 mg | sc-201057B | 250 mg | $239.00 | |||
Phosphatidic Acid, Dipalmitoyl, 500 mg | sc-201057A | 500 mg | $409.00 |