Phosalone (CAS 2310-17-0)
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Phosalone, a widely used organophosphate insecticide, holds significant applications in agricultural production. Phosalone primarily exists in solid form and demonstrates practical insolubility in water while maintaining a relatively neutral nature. Within cells, it is predominantly located in the membrane. Phosalone is considered potentially toxic. Chemically, phosalone belongs to the class of 1,3-benzoxazoles, featuring a [(diethoxyphosphorothioyl)sulfanyl]methyl group at the nitrogen atom, an oxo group at position 2, and a chloro group at position 6. As an organothiophosphate insecticide, it serves as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an EC 3.1.1.8 (cholinesterase) inhibitor, an acaricide, and an agrochemical. Its efficacy stems from its ability to target lipid peroxidation and various antioxidant enzymes, including superoxide dismutase, catalase, and glutathione peroxidase.
Phosalone (CAS 2310-17-0) References
- Role of reactive oxygen species in organophosphate insecticide phosalone toxicity in erythrocytes in vitro. | Altuntas, I., et al. 2003. Toxicol In Vitro. 17: 153-7. PMID: 12650668
- Photocatalytic degradation of an organophosphorus pesticide phosalone in aqueous suspensions of titanium dioxide. | Daneshvar, N., et al. 2004. J Environ Sci Health B. 39: 285-96. PMID: 15132335
- Effects of subchronic exposure to phosalone on oxidative stress and histopathological alterations in common carp (Cyprinus carpio, L., 1758). | Kaya, H., et al. 2013. J Toxicol Environ Health A. 76: 853-64. PMID: 24053362
- Phosalone-induced inflammation and oxidative stress in the colon: Evaluation and treatment. | Ghasemi-Niri, SF., et al. 2016. World J Gastroenterol. 22: 4999-5011. PMID: 27275092
- Effects of phosalone consumption via feeding with or without sodium bentonite on performance, blood metabolites and its transition to milk of Iranian Baluchi sheep. | Kazemi, M., et al. 2017. J Anim Sci Technol. 59: 10. PMID: 28515956
- Side effects of chlorantraniliprole, phosalone and spinosad on the egg parasitoid, Trichogramma brassicae. | Parsaeyan, E., et al. 2020. Ecotoxicology. 29: 1052-1061. PMID: 32448953
- Effects of phosalone plant pesticide on sperm parameters and sexual hormone levels in Wistar rats: An experimental study. | Mazaheri, F., et al. 2020. Int J Reprod Biomed. 18: 785-794. PMID: 33062924
- Degradation of phosalone by silver ion catalytic hydrolysis. | Hassan, J., et al. 2021. Toxicol Mech Methods. 31: 182-187. PMID: 33287621
- AChR is partly responsible in mice depressive-like behavior after Phosalone exposure. | Aliomrani, M., et al. 2021. Neurotoxicol Teratol. 84: 106957. PMID: 33539933
- Simultaneous detection and identification of thiometon, phosalone, and prothioconazole pesticides using a nanoplasmonic sensor array. | Koushkestani, M., et al. 2021. Food Chem Toxicol. 151: 112109. PMID: 33716053
- Nitrogen-doped carbon dots for dual-wavelength excitation fluorimetric assay for ratiometric determination of phosalone. | Liao, X., et al. 2021. Mikrochim Acta. 188: 247. PMID: 34244909
- Diethylphosphorus metabolites in serum and urine of persons poisoned by phosalone. | Vasilić, Z., et al. 1993. Chem Biol Interact. 87: 305-13. PMID: 8343988
- Reduction in phosalone residue levels during industrial dehydration of apples. | Mergnat, T., et al. 1995. Food Addit Contam. 12: 759-67. PMID: 8608850
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Phosalone, 100 mg | sc-250710 | 100 mg | $109.00 |