Date published: 2026-5-2

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Phomoxanthone A (CAS 359844-69-2)

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CAS Number:
359844-69-2
Purity:
≥97%
Molecular Weight:
750.70
Molecular Formula:
C38H38O16
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Phomoxanthone A is a biologically active compound, a dimeric xanthone isolated from the fungus Phomopsis species, which features a unique structural framework consisting of two connected xanthone cores. This dimerization enhances its chemical complexity and biological relevance, making it a subject of interest in various chemical and biochemical studies. The molecule is particularly noted for its potential to interact with multiple biological targets due to the presence of functional groups such as hydroxyls and ketones, which can engage in hydrogen bonding and other interactions with biomolecules. In research, Phomoxanthone A has been utilized to explore mechanisms of action such as enzyme inhibition and modulation of protein-protein interactions, providing insights into the cellular processes influenced by xanthones. Studies focusing on Phomoxanthone A help explain the role of fungal metabolites in their natural environments and contribute to a deeper understanding of the structural attributes of xanthones that correlate with biological activity. These investigations enhance the knowledge of natural product chemistry and aid in the design of novel compounds with potential applications in various fields of chemistry and biochemistry.


Phomoxanthone A (CAS 359844-69-2) References

  1. The tetrahydroxanthone-dimer phomoxanthone A is a strong inducer of apoptosis in cisplatin-resistant solid cancer cells.  |  Wang, C., et al. 2019. Bioorg Med Chem. 27: 115044. PMID: 31443950
  2. Carbamoyl-Phosphate Synthase 1 as a Novel Target of Phomoxanthone A, a Bioactive Fungal Metabolite.  |  Ceccacci, S., et al. 2020. Biomolecules. 10: PMID: 32498414
  3. Identification of Phomoxanthone A and B as Protein Tyrosine Phosphatase Inhibitors.  |  Yang, R., et al. 2020. ACS Omega. 5: 25927-25935. PMID: 33073119
  4. Elucidation of the Complete Biosynthetic Pathway of Phomoxanthone A and Identification of a Para-Para Selective Phenol Coupling Dimerase.  |  Yuan, SW., et al. 2022. Org Lett. 24: 3069-3074. PMID: 35442692
  5. Phomoxanthone A Targets ATP Synthase.  |  Ali, R., et al. 2022. Chemistry. 28: e202202397. PMID: 36082977
  6. Phomoxanthone A, Compound of Endophytic Fungi Paecilomyces sp. and Its Potential Antimicrobial and Antiparasitic.  |  Ramos, GDC., et al. 2022. Antibiotics (Basel). 11: PMID: 36289990
  7. Potent Bioactivity of Endophytic Fungi Isolated from Moringa oleifera Leaves.  |  Rehman, B., et al. 2022. Biomed Res Int. 2022: 2461021. PMID: 36567913
  8. Paecilins Q and R: Antifungal Chromanones Produced by the Endophytic Fungus Pseudofusicoccum stromaticum CMRP4328.  |  Iantas, J., et al. 2023. Planta Med. 89: 1178-1189. PMID: 36977488
  9. Potential of Secondary Metabolites of Diaporthe Species Associated with Terrestrial and Marine Origins.  |  Wei, W., et al. 2023. J Fungi (Basel). 9: PMID: 37108907
  10. Robust, Enantioselective Construction of Challenging, Biologically Relevant Tertiary Ether Stereocenters.  |  Guan, Y., et al. 2021. ACS Catal. 11: 6325-6333. PMID: 37636585

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phomoxanthone A, 1 mg

sc-364127
1 mg
$180.00