Date published: 2025-12-29

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Phenylzinc bromide solution (CAS 38111-44-3)

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CAS Number:
38111-44-3
Molecular Weight:
222.42
Molecular Formula:
C6H5BrZn
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.

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Phenylzinc bromide solution is used as a nucleophile in organic synthesis. It functions as a strong base and a source of phenyl anions, which can undergo nucleophilic addition reactions with a variety of electrophiles. In the presence of suitable substrates, the phenylzinc bromide solution can participate in cross-coupling reactions, such as the formation of carbon-carbon bonds through palladium-catalyzed coupling reactions. Phenylzinc Bromide Solution′s mechanism of action involves the transfer of the phenyl group to the electrophilic center of the substrate, leading to the formation of new carbon-carbon or carbon-heteroatom bonds.


Phenylzinc bromide solution (CAS 38111-44-3) References

  1. Well-Defined Ni(0) and Ni(II) Complexes of Bicyclic (Alkyl)(Amino)Carbene (Me BICAAC): Catalytic Activity and Mechanistic Insights in Negishi Cross-Coupling Reaction.  |  Thakur, SK., et al. 2022. Chemistry. 28: e202202237. PMID: 35899619
  2. Palladium-Catalyzed Cross-Coupling of Organozinc Bromides with Aryl Iodides in Perfluorinated Solvents  |  Dipl.-Chem. Bodo Betzemeier, Prof. Dr. Paul Knochel. 1997. Angewandte Chemie International Edition. 36: 2623-2624.
  3. Palladium(0)-Catalyzed Cross-Couplings of 2-Bromophosphinine  |  Nataliya Kostenko, Cecilia Ericsson, Magnus Engqvist, Susana Villa Gonzalez, Annette Bayer. 2013. European Journal of Organic Chemistry. 2013: 4756-4759.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phenylzinc bromide solution, 50 ml

sc-236385
50 ml
$128.00
US: Only available in the US