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Phenylphosphorodiamidate (CAS 7450-69-3)

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Alternate Names:
phosphoric phenyl ester diamide
CAS Number:
7450-69-3
Purity:
≥95%
Molecular Weight:
172.12
Molecular Formula:
C6H9N2O2P
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Phenylphosphorodiamidate (PPD) is an organophosphate compound noted for its multipurpose use across various scientific research applications. Its versatility lies in its capacity for synthesizing diverse compounds and exploring biochemical and physiological effects. Phenylphosphorodiamidate is extensively used in a broad range of scientific research applications, including the synthesis of various compounds and the examination of biochemical and physiological impacts. It′s also employed in the analysis of biological samples such as proteins and nucleic acids, and in refining novel analytical techniques like mass spectrometry and chromatography. Phenylphosphorodiamidate′s mode of action remains partially unknown. It′s hypothesized that Phenylphosphorodiamidate interacts with particular proteins and enzymes in the body, modifying their functions. Such interactions could lead to a range of biochemical and physiological effects, contingent on the specific proteins and enzymes that Phenylphosphorodiamidate binds to.


Phenylphosphorodiamidate (CAS 7450-69-3) References

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  2. Amino Acid Utilization in Seeds of Loblolly Pine during Germination and Early Seedling Growth (I. Arginine and Arginase Activity).  |  King, JE. and Gifford, DJ. 1997. Plant Physiol. 113: 1125-1135. PMID: 12223664
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  4. Elimination of the adverse effects of urea fertilizer on seed germination, seedling growth, and early plant growth in soil.  |  Bremner, JM. and Krogmeier, MJ. 1988. Proc Natl Acad Sci U S A. 85: 4601-4. PMID: 16593951
  5. Evidence that the adverse effect of urea fertilizer on seed germination in soil is due to ammonia formed through hydrolysis of urea by soil urease.  |  Bremner, JM. and Krogmeier, MJ. 1989. Proc Natl Acad Sci U S A. 86: 8185-8. PMID: 16594076
  6. Phytotoxicity of foliar-applied urea.  |  Krogmeier, MJ., et al. 1989. Proc Natl Acad Sci U S A. 86: 8189-91. PMID: 16594077
  7. Jack bean urease: the effect of active-site binding inhibitors on the reactivity of enzyme thiol groups.  |  Krajewska, B. and Zaborska, W. 2007. Bioorg Chem. 35: 355-65. PMID: 17418881
  8. Structural characteristics of phosphoramide derivatives as urease inhibitors. Requirements for activity.  |  Font, M., et al. 2008. J Agric Food Chem. 56: 8451-60. PMID: 18729463
  9. Competitive inhibitors of Klebsiella aerogenes urease. Mechanisms of interaction with the nickel active site.  |  Todd, MJ. and Hausinger, RP. 1989. J Biol Chem. 264: 15835-42. PMID: 2674118
  10. Purification, characterization, and genetic analysis of Mycobacterium tuberculosis urease, a potentially critical determinant of host-pathogen interaction.  |  Clemens, DL., et al. 1995. J Bacteriol. 177: 5644-52. PMID: 7559354
  11. Essential role of urease in germination of nitrogen-limited Arabidopsis thaliana seeds.  |  Zonia, LE., et al. 1995. Plant Physiol. 107: 1097-103. PMID: 7770520
  12. X-ray absorption spectroscopy study of native and phenylphosphorodiamidate-inhibited Bacillus pasteurii urease.  |  Benini, S., et al. 1996. Eur J Biochem. 239: 61-6. PMID: 8706719
  13. Crystallization and preliminary high-resolution X-ray diffraction analysis of native and beta-mercaptoethanol-inhibited urease from Bacillus pasteurii.  |  Benini, S., et al. 1998. Acta Crystallogr D Biol Crystallogr. 54: 409-12. PMID: 9761912

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phenylphosphorodiamidate, 10 g

sc-272022
10 g
$255.00