Phenylhexyl isothiocyanate CAS: 133920-06-6
MF: C13H17NS
MW: 219.35
Used to study tumorigenesis in mice and rats.

Phenylhexyl isothiocyanate (CAS 133920-06-6)

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Application: Used to study tumorigenesis in mice and rats
CAS Number: 133920-06-6
Purity: >98%
Molecular Weight: 219.35
Molecular Formula: C13H17NS
* Refer to Certificate of Analysis for lot specific data (including water content).
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Phenylhexyl isothiocyanate is a chemopreventive agent in mouse lung, however, it has been found to enhance colon and esophageal tumorigenesis in rats.


References

1. Morse, M A., et al., 1991. Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice. Cancer research. 51(7): 1846-50. PMID: 2004368
2. Stoner, G D., et al., 1995. Enhancement of esophageal carcinogenesis in male F344 rats by dietary phenylhexyl isothiocyanate. Carcinogenesis. 16(10): 2473-6. PMID: 7586154
3. Rao, C V., et al., 1995. Enhancement of experimental colon carcinogenesis by dietary 6-phenylhexyl isothiocyanate. Cancer research. 55(19): 4311-8. PMID: 7671241

Physical State :
Liquid
Solubility :
Soluble in organic solvent, and chloroform.
Storage :
Store at 4° C
Melting Point :
79.32° C (Predicted)
Boiling Point :
346.07° C at 760 mmHg (Predicted)
Density :
0.97 g/mL (Predicted)
Refractive Index :
n20D 1.53 (Predicted)
IC50 :
UACC-903: IC50 = 15 µM (human); PC-3: IC50 = 17 µM (human); MDA-MB-231: IC50 = 24 µM (human); T98G: IC50 = 26 µM (human); HT-1080: IC50 = 29 µM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
114757
MDL Number :
MFCD02752403
SMILES :
C1=CC=C(C=C1)CCCCCCN=C=S

Download SDS (MSDS)

Certificate of Analysis

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