Date published: 2026-4-5

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Phenylglyoxylic Acid (CAS 611-73-4)

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Alternate Names:
2-Oxo-2-phenylethanoic Acid; Benzoylformic Acid; α-Ketophenylacetic Acid
CAS Number:
611-73-4
Molecular Weight:
150.13
Molecular Formula:
C8H6O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Phenylglyoxylic Acid is an essential organic compound, appearing as a colorless solid. Its versatility makes it valuable in a variety of applications. Phenylglyoxylic Acid plays a vital role in the production of polymers and resins. The scientific community has devoted extensive research to exploring the potential applications of Phenylglyoxylic Acid. In vitro studies have shed light on its mechanisms of action regarding environmental toxins, offering valuable insights into cellular processes. Although the precise mechanism of action of Phenylglyoxylic Acid remains elusive, researchers believe it acts through the binding to specific enzymes, effectively blocking their activity. This inhibition, in turn, impacts various cellular processes, including cell growth and proliferation.


Phenylglyoxylic Acid (CAS 611-73-4) References

  1. Simultaneous determination of phenylglyoxylic acid, mandelic acid, styrene glycol and hippuric acid in primary culture of rat hepatocytes incubate by high-performance liquid chromatography.  |  Wang, JZ., et al. 2007. Biomed Chromatogr. 21: 497-501. PMID: 17357177
  2. [Determination of cotinine, phenylglyoxylic acid and mandelic acid in human urine by GC/MS].  |  Wu, YY., et al. 2009. Zhejiang Da Xue Xue Bao Yi Xue Ban. 38: 229-34. PMID: 19504629
  3. Plant-mediated stereoselective biotransformation of phenylglyoxylic acid esters.  |  Maczka, WK., et al. 2014. Z Naturforsch C J Biosci. 69: 309-16. PMID: 25265851
  4. [Determination of phenylglyoxylic acid and mandelic acid in urine by high performance liquid chromatography method].  |  Cui, SW., et al. 2017. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 35: 774-776. PMID: 29294557
  5. Photogenerated Radical in Phenylglyoxylic Acid for in Vivo Hyperpolarized 13C MR with Photosensitive Metabolic Substrates.  |  Marco-Rius, I., et al. 2018. J Am Chem Soc. 140: 14455-14463. PMID: 30346733
  6. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005-2006 and 2011-2012.  |  Capella, KM., et al. 2019. Environ Res. 171: 101-110. PMID: 30660916
  7. One-Pot Synthesis of Phenylglyoxylic Acid from Racemic Mandelic Acids via Cascade Biocatalysis.  |  Tang, CD., et al. 2019. J Agric Food Chem. 67: 2946-2953. PMID: 30807132
  8. Phenylglyoxylic Acid: An Efficient Initiator for the Photochemical Hydrogen Atom Transfer C-H Functionalization of Heterocycles.  |  Papadopoulos, GN., et al. 2020. ChemSusChem. 13: 5934-5944. PMID: 32833347
  9. Ultrastable Tb-Organic Framework as a Selective Sensor of Phenylglyoxylic Acid in Urine.  |  Jia, P., et al. 2021. ACS Appl Mater Interfaces. 13: 33546-33556. PMID: 34235930
  10. Photochemical C-H acetalization of O-heterocycles utilizing phenylglyoxylic acid as the photoinitiator.  |  Koutoulogenis, GS., et al. 2022. Photochem Photobiol Sci. 21: 687-694. PMID: 34750786
  11. Two novel zinc-based MOFs as luminescence sensors to detect phenylglyoxylic acid.  |  Song, D., et al. 2022. Dalton Trans. 51: 16266-16273. PMID: 36218122
  12. Determination of mandelic acid and phenylglyoxylic acid in the urine and its use in monitoring of styrene exposure.  |  Chua, SC., et al. 1993. J Anal Toxicol. 17: 129-32. PMID: 8336484
  13. Isotachophoretic analysis of mandelic acid, phenylglyoxylic acid, hippuric acid and methylhippuric acid in urine after occupational exposure to styrene, toluene and/or xylene.  |  Sollenberg, J. and Baldesten, A. 1977. J Chromatogr. 132: 469-76. PMID: 885945

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Phenylglyoxylic Acid, 5 g

sc-212553
5 g
$39.00