Phalloidin-tetramethylrhodamine B isothiocyanate MF: C62H72N12O12S4
MW: 1305.57

Phalloidin-tetramethylrhodamine B isothiocyanate

Phalloidin-tetramethylrhodamine B isothiocyanate is rated 5.0 out of 5 by 1.
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Alternate Names: Phalloidin-tetramethylrhodamine B isothiocyanate is also known as Phalloidin-TRITC.
Application: Phalloidin-tetramethylrhodamine B isothiocyanate is a fluorescent phallotoxin that can be used to identify filamentous actin and label actin microfilaments.
Molecular Weight: 1305.57
Molecular Formula: C62H72N12O12S4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits
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Phalloidin-tetramethylrhodamine B isothiocyanate is a fluorescent phalloidin (sc-202763) derivative that can be used to identify filamentous actin. Phalloidin-tetramethylrhodamine B isothiocyanate binds polymeric F actin, stabilizing it and interfering with the function of actin-rich structures. The rhodamine moiety of Phalloidin-tetramethylrhodamine B isothiocyanate then allows for visualization of F-actin through fluorescence. In addition to labeling actin microfilaments for fluorescence miscroscopy, Phalloidin-tetramethylrhodamine B isothiocyanate can stain cells during immunocytochemical and cytochemical analysis.


References

1. Faulstich, H., et al. 1983. Exp. Cell Res. 144: 73-82. PMID: 6840214

2. Waggoner, A., et al. 1989. Methods Cell Biol. 30: 449-478. PMID: 2648118

Physical State :
Solid
Solubility :
Soluble in water (0.5%), methanol, ethanol, butanol, and pyridine.
Storage :
Store at -20° C
Fluoresence :
λex 540-545 nm, λem 570-573 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
MDL Number :
MFCD00278840

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Certificate of Analysis

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Phalloidin-tetramethylrhodamine B isothiocyanate  Product Citations

See how others have used Phalloidin-tetramethylrhodamine B isothiocyanate. Click on the entry to view the PubMed entry .

Citations 1 to 10 of 14 total

PMID: # 33927296  Pisko, J.|Špirková, A.|Čikoš, Š.|Olexiková, L.|Kovaříková, V.|Šefčíková, Z.|Fabian, D.| et al. 2021. Sci Rep. 11: 9228.

PMID: # 31225977  Jana, A.|Nookaew, I.|Singh, J.|Behkam, B.|Franco, AT.|Nain, AS.| et al. 2019. FASEB J. fj201900131R.

PMID: # 28099467  Barnes, L.|Saurat, JH.|Kaya, G.| et al. 2017. PLoS ONE. 12: e0169452.

PMID: # 27081925  Waisbourd-Zinman, O.|Koh, H.|Tsai, S.|Lavrut, PM.|Dang, C.|Zhao, X.|Pack, M.|Cave, J.|Hawes, M.|Koo, KA.|Porter, JR.|Wells, RG.| et al. 2016. Hepatology. 64: 880-93.

PMID: # 23223147  Barnes, L. et al. 2013. J. Invest. Dermatol. 133: 1017-1026.

Eliane Antoniolia et al. 2013. Materials Science and Engineering: C. 33: 641-647.

PMID: # 25427468  Antonioli, E. et al. 2013. Materials science & engineering. C, Materials for biological applications. 33: 641-7.

PMID: # 17415732  Chan, EW. et al. 2007. Angew. Chem. Int. Ed. Engl. 46: 3881-3884.

PMID: # 32324228  Nucleic Acids Res.

PMID: # 32371929  Sci Rep. 10: 7599.

Citations 1 to 10 of 14 total

What is the recommended volume to resuspend the product?

Asked by: Christian_Monroy
I found out a little more! Ideal solvent is: 0.5 mg/ml in methanol.
Answered by: Tech Service
Date published: 2019-01-07

What is the solubility in methanol?

Asked by: SCchem16
Thank you for your question. This chemical, Phalloidin-tetramethylrhodamine B isothiocyanate, is soluble in methanol up to 0.5mg/mL.
Answered by: Chemical Support 2
Date published: 2017-03-02
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Rated 5 out of 5 by from Various publications cite the use of the Various publications cite the use of the fluorescent phallotoxin, phalloidin-tetramethylrhodamine B isothiocyanate, to identify filamentous actin. -SCBT Publication Review
Date published: 2015-01-29
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