Molecular structure of PHA-793887, CAS Number: 718630-59-2
PHA-793887 (CAS 718630-59-2)
Application:
PHA-793887 is a novel pan-Cdk inhibitor inactive against 34 other kinases
CAS Number:
718630-59-2
Molecular Weight:
361.48
Molecular Formula:
C19H31N5O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
PHA-793887 is a novel pan-Cdk inhibitor, including Cdk1, Cdk2, Cdk4, Cdk5, Cdk7, and Cdk9 with IC50 in the 5 to 140 nM range. PHA-793887 is inactive against 34 other kinases representative of all kinase families, in particular c-abl, c-kit, lck, and TRKA with IC50>10 mM. PHA-793887 shows anti-proliferative activity against several solid tumor cell lines, with IC50
Inhibitor of:
casein kinase Iα, Cdk, Cdk6, Cdk9, Cks1, cyclin δ-1, cyclin A, Cyclin A1, cyclin B, cyclin C, cyclin D3, cyclin G2, cyclin I, cyclin J, FAM127B, NIF3L1 BP1, Npl4, p14 ARF/p16, p57, Sic1, and UHMK1.Activator of:
SOLO.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PHA-793887, 5 mg | sc-364580 | 5 mg | $189.00 | |||
PHA-793887, 10 mg | sc-364580A | 10 mg | $432.00 |