PGA2 (Prostaglandin A2) (CAS 13345-50-1)
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PGA2 (Prostaglandin A2) may act to be formed by the dehydration of PGE2 (Prostaglandin E2 sc-201225) in vitro, and is believed to be formed via PGE2 in vivo. Prostaglandins are a family of biologically potent lipids from membrane phospholipids comprised of a C20-unsaturated fatty acid containing a cyclopentane ring. PGA2 may act to display antitumor activity, to induce gamma-glutamylcysteine synthetase and apoptosis in L-1210 cells, as well as inhibit growth and stimulate differentiation of Friend erythroleukaemia cells and cause cell cycle arrest at G1 phase and inhibit viral replication at non-toxic doses. According to a recent study, PGA2 activates intrinsic apoptotic pathways by directly stimulating mitochondrial outer membrane permeabilization to release Cytochrome C.
PGA2 (Prostaglandin A2) (CAS 13345-50-1) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PGA2 (Prostaglandin A2), 1 mg | sc-201215 | 1 mg | $210.00 | |||
PGA2 (Prostaglandin A2), 10 mg | sc-201215A | 10 mg | $410.00 |