Date published: 2025-11-5

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PF-622 (CAS 898235-65-9)

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Application:
PF-622 is a novel, potent and selective inhibitor of FAAH (fatty acid amide hydrolase)
CAS Number:
898235-65-9
Molecular Weight:
346.4
Molecular Formula:
C21H22N4O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Is a potent, irreversible, time-dependent FAAH inhibitor with IC50 values 0.99 and 0.033 µM when preincubated with human recombinant FAAH for 5 and 60 minutes, respectively.1 Activity-based profiling of various human and murine tissue proteome samples showed that it is highly selective for FAAH relative to other serine hydrolases, showing no discernable off-site activity up to 500 µM.1


PF-622 (CAS 898235-65-9) References

1 Ahn, K., Johnson, D.S., Fitzgerald, L.R., et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry 46 13019-13030 (2007).

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

PF-622, 1 mg

sc-205431
1 mg
$90.00

PF-622, 5 mg

sc-205431A
5 mg
$80.00