Molecular structure of PF-429242, CAS Number: 947303-87-9
PF-429242 (CAS 947303-87-9)
Alternate Names:
(R)-4-((Diethylamino)methyl)-N-(2-methoxyphenethyl)-N-(pyrrolidin-3-yl)benzamide PF 429242 PF429242 49WB3OA7VN
CAS Number:
947303-87-9
Molecular Weight:
409.60
Molecular Formula:
C25H35N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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PF-429242 (CAS 947303-87-9) References
- Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242. | Pasquato, A., et al. 2012. Virology. 423: 14-22. PMID: 22154237
- SKI-1/S1P inhibition: a promising surrogate to statins to block hepatitis C virus replication. | Blanchet, M., et al. 2012. Antiviral Res. 95: 159-66. PMID: 22626636
- SKI-1/S1P inhibitor PF-429242 impairs the onset of HCV infection. | Blanchet, M., et al. 2015. Antiviral Res. 115: 94-104. PMID: 25573299
- PF-429242, a Subtilisin Inhibitor, Is Effective in vitro Against Leishmania infantum. | Machado, PA., et al. 2021. Front Microbiol. 12: 583834. PMID: 33584607
- The novel therapeutic target and inhibitory effects of PF-429242 against Zika virus infection. | Raini, SK., et al. 2021. Antiviral Res. 192: 105121. PMID: 34175321
- SREBP1 site 1 protease inhibitor PF-429242 suppresses renal cell carcinoma cell growth. | Wang, TB., et al. 2021. Cell Death Dis. 12: 717. PMID: 34285190
- Corrigendum to 'The novel therapeutic target and inhibitory effects of PF-429242 against Zika virus infection' [Antivir. Res. vol 192 (2021) 1-13/105121]. | Raini, SK., et al. 2022. Antiviral Res. 199: 105245. PMID: 35120757
- Subtilisin of Leishmania amazonensis as Potential Druggable Target: Subcellular Localization, In Vitro Leishmanicidal Activity and Molecular Docking of PF-429242, a Subtilisin Inhibitor. | Gomes, PS., et al. 2022. Curr Issues Mol Biol. 44: 2089-2106. PMID: 35678670
- Evaluation of aminopyrrolidine amide to improve chloride transport in CFTR-defective cells. | Huguet, F., et al. 2022. Bioorg Med Chem Lett. 72: 128866. PMID: 35752380
- PF-429242 exhibits anticancer activity in hepatocellular carcinoma cells via FOXO1-dependent autophagic cell death and IGFBP1-dependent anti-survival signaling. | Lin, JC., et al. 2023. Am J Cancer Res. 13: 4125-4144. PMID: 37818050
Inhibitor of:
C1GALT1, N-myristoyltransferase 2, NPC Marker, ORP-8, rotavirus C vp4, rotavirus NSP4, SCAP, SERINC4, SKI-1, SREBP-2, Syndecan-4, ZDHHC12, ZDHHC15, ZDHHC19, ZDHHC24, ZDHHC5, ZDHHC6, and ZNRF2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PF-429242, 5 mg | sc-507498 | 5 mg | $176.00 |