Date published: 2025-10-2

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Perfluorohexadecanoic acid (CAS 67905-19-5)

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Alternate Names:
Perfluoropalmitic acid
CAS Number:
67905-19-5
Molecular Weight:
814.12
Molecular Formula:
C16HF31O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Perfluorohexadecanoic acid is a perfluorinated fatty acid employed as a diagnostic tool for detecting human serum albumin. Its binding with protease activity triggers fluorescence release, enabling the detection process. Moreover, this molecule serves as a molecular docking agent in vitro, forming hydrogen bonds with fatty acids and aromatic hydrocarbons through its hydrogen bond interaction with the carbonyl and alkylthio groups.


Perfluorohexadecanoic acid (CAS 67905-19-5) References

  1. Properties of two-component Langmuir monolayer of single chain perfluorinated carboxylic acids with dipalmitoylphosphatidylcholine (DPPC).  |  Nakahara, H., et al. 2005. Colloids Surf B Biointerfaces. 41: 285-98. PMID: 15748824
  2. Perfluorinated compounds in the Pearl River and Yangtze River of China.  |  So, MK., et al. 2007. Chemosphere. 68: 2085-95. PMID: 17368725
  3. [Perfluorinated compounds in potable water].  |  Rostkowski, P., et al. 2008. Rocz Panstw Zakl Hig. 59: 283-92. PMID: 19143425
  4. Miscibility behavior of two-component monolayers at the air-water interface: perfluorocarboxylic acids and DMPE.  |  Yokoyama, H., et al. 2009. J Colloid Interface Sci. 337: 191-200. PMID: 19481762
  5. Miscibility and phase behavior of DPPG and perfluorocarboxylic acids at the air-water interface.  |  Yokoyama, H., et al. 2009. Chem Phys Lipids. 161: 103-14. PMID: 19560445
  6. Nanometer-sized domains in Langmuir-Blodgett films for patterning SiO2.  |  Kataoka, S., et al. 2010. Langmuir. 26: 6161-3. PMID: 20369867
  7. Fluorinated alkyl compounds including long chain carboxylic acids in wild bird livers from Japan.  |  Guruge, KS., et al. 2011. Chemosphere. 83: 379-84. PMID: 21190717
  8. Unique physicochemical properties of perfluorinated compounds and their bioconcentration in common carp Cyprinus carpio L.  |  Inoue, Y., et al. 2012. Arch Environ Contam Toxicol. 62: 672-80. PMID: 22127646
  9. Human dietary exposure to perfluoroalkyl substances in Catalonia, Spain. Temporal trend.  |  Domingo, JL., et al. 2012. Food Chem. 135: 1575-82. PMID: 22953896
  10. Structure-activity relations in binding of perfluoroalkyl compounds to human thyroid hormone T3 receptor.  |  Ren, XM., et al. 2015. Arch Toxicol. 89: 233-42. PMID: 24819616
  11. Perfluorohexadecanoic acid increases paracellular permeability in endothelial cells through the activation of plasma kallikrein-kinin system.  |  Liu, QS., et al. 2018. Chemosphere. 190: 191-200. PMID: 28987408
  12. Per- and polyfluoroalkyl substances in source and treated drinking waters of the United States.  |  Boone, JS., et al. 2019. Sci Total Environ. 653: 359-369. PMID: 30412881
  13. Risk Assessment of Per- and Polyfluoroalkyl Substance Mixtures: A Relative Potency Factor Approach.  |  Bil, W., et al. 2021. Environ Toxicol Chem. 40: 859-870. PMID: 32729940

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Perfluorohexadecanoic acid, 5 g

sc-264048
5 g
$251.00

Perfluorohexadecanoic acid, 25 g

sc-264048A
25 g
$679.00

Perfluorohexadecanoic acid, 100 g

sc-264048B
100 g
$2405.00