Molecular structure of Pentisomide, CAS Number: 78833-03-1
Pentisomide (CAS 78833-03-1)
Application:
Pentisomide is a sodium channel blocker
CAS Number:
78833-03-1
Molecular Weight:
319.48
Molecular Formula:
C19H33N3O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
Pentisomide is a sodium channel blocker that is a derivative of disopyramide. Pentisomide is also an antiarrhythmic (class I).
Pentisomide (CAS 78833-03-1) References
- Antiarrhythmic and electrophysiological effects of amiodarone, lignocaine, and penticainide in anaesthetised rats. | Li, JY. and Northover, BJ. 1992. Cardiovasc Res. 26: 1116-20. PMID: 1291090
- Selectivity of class I antiarrhythmic agents, disopyramide, pirmenol, and pentisomide for peripheral muscarinic M2 and M3 receptors. | Endou, M., et al. 1992. J Cardiovasc Pharmacol. 19: 674-81. PMID: 1381764
- Electrophysiology and long-term efficacy of pentisomide in patients with supraventricular tachycardia. | Kühlkamp, V., et al. 1992. Int J Cardiol. 36: 69-79. PMID: 1428255
- Effects of pentisomide and E-4031 on canine atrial flutter due to reentry: a comparative study with disopyramide and propafenone. | Inoue, H., et al. 1991. J Cardiovasc Pharmacol. 18: 137-43. PMID: 1719282
- [Pharmacological analysis of drug interactions of disopyramide and its congeners with peripheral muscarinic acetylcholine receptors]. | Endou, M. 1991. Hokkaido Igaku Zasshi. 66: 677-93. PMID: 1959843
- High-performance liquid chromatographic method for the simultaneous determination of pentisomide and its major metabolite N-desisopropylpentisomide in plasma, urine and tissues using solid-phase extraction. | Plomp, TA. and Buijs, MJ. 1993. J Chromatogr. 612: 123-35. PMID: 8454692
- Antiarrhythmic effect related to the plasma concentration of pentisomide in vivo and the antiarrhythmic-concentration relationship in vitro. | Hachisu, M., et al. 1995. Drugs Exp Clin Res. 21: 145-51. PMID: 8529527
- Quantitation of pentisomide and its metabolite by high-pressure liquid chromatography in human serum. | Mewis, C., et al. 1996. J Chromatogr Sci. 34: 161-5. PMID: 8901131
- Class I antiarrhythmic drugs alter the severity of myocardial stunning by modulating ATP-sensitive K+ channels in guinea pig ventricular muscles. | Shigematsu, S., et al. 1998. Naunyn Schmiedebergs Arch Pharmacol. 357: 283-90. PMID: 9550300
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pentisomide, 2.5 mg | sc-219569 | 2.5 mg | $430.00 |