Date published: 2025-10-31

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Pentafluoropropionic acid (CAS 422-64-0)

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CAS Number:
422-64-0
Molecular Weight:
164.03
Molecular Formula:
C3HF5O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pentafluoropropionic acid, also known as PFPA, is an organic compound characterized by its colorless liquid form and pungent odor. PFPA belongs to the family of perfluorinated carboxylic acids. The extensive utilization of Pentafluoropropionic acid in scientific research encompasses various domains. Firstly, Pentafluoropropionic acid serves as a catalyst in organic synthesis, facilitating the creation of fluorinated compounds such as fluoroalcohols, perfluoroalkyl iodides, and perfluoroalkyl sulfonates. Furthermore, Pentafluoropropionic acid assumes the role of a reagent in analytical chemistry, aiding in the detection and quantification of organic compounds, including fatty acids and alcohols, in aqueous samples. In organic synthesis, Pentafluoropropionic acid acts as a Lewis acid, establishing covalent bonds with the electron pair of a Lewis base, thereby giving rise to new molecules. In the domain of analytical chemistry, Pentafluoropropionic acid operates as an ion exchange resin, facilitating the exchange of ions with other ions present in a solution, resulting in the formation of novel molecules. In the field of biochemistry, Pentafluoropropionic acid showcases its ability as a fluorinating agent, facilitating the incorporation of fluorine into biomolecules through the formation of covalent bonds.


Pentafluoropropionic acid (CAS 422-64-0) References

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  5. Kinetics and mechanism of the reaction of fluorine atoms with pentafluoropropionic acid.  |  Vasiliev, ES., et al. 2014. J Phys Chem A. 118: 4013-8. PMID: 24819330
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pentafluoropropionic acid, 10 g

sc-250668
10 g
$56.00