Date published: 2025-10-21

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Pentadecanolide (CAS 106-02-5)

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Alternate Names:
1-Oxa-2-cyclohexadecanone
Application:
Pentadecanolide is a monomer used to make PGA-co-pentadecalactone polymers
CAS Number:
106-02-5
Purity:
≥97%
Molecular Weight:
240.38
Molecular Formula:
C15H28O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pentadecanolide, a cyclic fatty acid lactone, has garnered significant attention in scientific research, particularly in the fields of chemical ecology, fragrance chemistry, and materials science. Its mechanism of action primarily revolves around its ability to act as a semiochemical, influencing behaviors and interactions between organisms. In research, pentadecanolide serves as a pheromone or odorant compound, playing roles in communication, mate recognition, and territorial marking among various species. Studies have focused on elucidating the chemical signals and receptors involved in pentadecanolide-mediated behaviors, shedding light on the mechanisms underlying animal communication and social interactions. Additionally, pentadecanolide is utilized in fragrance chemistry, where its unique odor profile contributes to perfumes, cosmetics, and household products. Research efforts have explored the synthesis of pentadecanolide derivatives with enhanced olfactory properties and stability for applications in the fragrance industry. Furthermore, pentadecanolide-based materials exhibit promising properties for use in polymer science, including as plasticizers, lubricants, and additives in various industrial applications. Investigations into the synthesis and characterization of pentadecanolide-based materials have highlighted their potential as sustainable and biocompatible alternatives to traditional petroleum-derived compounds. Overall, pentadecanolide presents a versatile compound with diverse research applications, ranging from chemical ecology to materials science, offering opportunities for innovation and advancement in multiple scientific disciplines.


Pentadecanolide (CAS 106-02-5) References

  1. A concise synthesis of the fully functional lactide core of cycloviracin B with implications for the structural assignment of related glycolipids.  |  Fürstner, A., et al. 2002. J Am Chem Soc. 124: 1168-9. PMID: 11841275
  2. Estrogenic activity of musk fragrances detected by the E-screen assay using human mcf-7 cells.  |  Bitsch, N., et al. 2002. Arch Environ Contam Toxicol. 43: 257-64. PMID: 12202919
  3. Synthesis of omega-hydroxy carboxylic acids and alpha,omega-dimethyl ketones using alpha,omega-diols as alkylating agents.  |  Iuchi, Y., et al. 2010. J Org Chem. 75: 1803-6. PMID: 20121069
  4. A practical synthesis of long-chain iso-fatty acids (iso-C12-C19) and related natural products.  |  Richardson, MB. and Williams, SJ. 2013. Beilstein J Org Chem. 9: 1807-12. PMID: 24062846
  5. In vitro evaluation of the metabolic stability of nine fragrance chemicals in trout and human hepatocytes.  |  Weeks, J., et al. 2020. J Appl Toxicol. 40: 1421-1434. PMID: 32488907
  6. Comparative assessment of marine weathering of ROP-derived biopolymers against conventional plastics.  |  Rodgers, K., et al. 2021. Mar Pollut Bull. 167: 112272. PMID: 33774483
  7. Reverse Chemical Ecology Suggests Putative Primate Pheromones.  |  Zaremska, V., et al. 2022. Mol Biol Evol. 39: PMID: 34897488
  8. Calcium Glycerolate Catalyst Derived from Eggshell Waste for Cyclopentadecanolide Synthesis.  |  Cheng, H., et al. 2021. Front Chem. 9: 770247. PMID: 34957045
  9. GC-MS analysis of aqueous extract of Nymphaea lotus and ameliorative potential of its biosynthesized gold nanoparticles against cadmium-induced kidney damage in rats.  |  Adebayo, VA., et al. 2023. Heliyon. 9: e17124. PMID: 37484424
  10. Thermally Stable and Chemically Recyclable Poly(ketal-ester)s Regulated by Floor Temperature.  |  Meng, XB., et al. 2024. J Am Chem Soc. 146: 15428-15437. PMID: 38795044

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pentadecanolide, 25 g

sc-215686
25 g
$37.00

Pentadecanolide, 100 g

sc-215686A
100 g
$188.00