Date published: 2025-10-15

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Pentadecafluorooctanoic acid (CAS 335-67-1)

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Alternate Names:
Perfluorooctanoic acid; PFOA
CAS Number:
335-67-1
Purity:
≥95%
Molecular Weight:
414.07
Molecular Formula:
C8HF15O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Pentadecafluorooctanoic acid (PFOA) is a synthetic chemical compound belonging to the class of perfluorinated alkyl substances (PFAS). It is a fully fluorinated carboxylic acid with the chemical formula C8HF15O2. Pentadecafluorooctanoic acid has been used in various industrial applications, including as a surfactant, emulsifier, and surface treatment agent. It was historically used in the production of non-stick coatings for cookware, water-repellent coatings for textiles, and fire-fighting foams.


Pentadecafluorooctanoic acid (CAS 335-67-1) References

  1. Comparative hepatic gene expression profiling of rats treated with 1H,1H,2H,2H-heptadecafluorodecan-1-ol or with pentadecafluorooctanoic acid.  |  Nilsen, AJ., et al. 2008. Physiol Genomics. 34: 285-303. PMID: 18544661
  2. Endocrine disrupting properties of perfluorooctanoic acid.  |  White, SS., et al. 2011. J Steroid Biochem Mol Biol. 127: 16-26. PMID: 21397692
  3. Differential toxicity between perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA).  |  Tsuda, S. 2016. J Toxicol Sci. 41: SP27-SP36. PMID: 28003637
  4. Photodegradation of perfluorooctanoic acid by graphene oxide-deposited TiO2 nanotube arrays in aqueous phase.  |  Park, K., et al. 2018. J Environ Manage. 218: 333-339. PMID: 29689536
  5. Male reproductive toxicity of perfluorooctanoate (PFOA): Rodent studies.  |  Wang, Z., et al. 2021. Chemosphere. 270: 128608. PMID: 33081999
  6. Perfluorooctanoic acid triggers oxidative stress in anaerobic digestion of sewage sludge.  |  Jiao, Y., et al. 2022. J Hazard Mater. 424: 127418. PMID: 34879508
  7. Perfluorooctanoic acid (PFOA)-induced alterations of biomolecules in the wetland plant Alismaorientale.  |  Wang, TT., et al. 2022. Sci Total Environ. 820: 153302. PMID: 35066035
  8. Simultaneous determination of perfluorooctanoic acid and perfluorooctanesulfonic acid in Korean sera using LC-MS/MS.  |  Heo, DG., et al. 2022. J Chromatogr B Analyt Technol Biomed Life Sci. 1192: 123138. PMID: 35114474
  9. Perfluorooctanoic acid affects mouse brain and liver tissue through oxidative stress.  |  Endirlik, BÜ., et al. 2022. Arh Hig Rada Toksikol. 73: 148-157. PMID: 35792765
  10. Perfluorooctanoic acid alternatives hexafluoropropylene oxides exert male reproductive toxicity by disrupting blood-testis barrier.  |  Peng, BX., et al. 2022. Sci Total Environ. 846: 157313. PMID: 35842142
  11. Perfluorooctanoic Acid Affects Thyroid Follicles in Common Carp (Cyprinus carpio).  |  Manera, M., et al. 2022. Int J Environ Res Public Health. 19: PMID: 35897426
  12. Perfluorooctanoic acid-induced developmental cardiotoxicity in chicken embryo: Roles of miR-490-5p.  |  Guo, Y., et al. 2022. Environ Pollut. 312: 120022. PMID: 36028080
  13. Perfluorooctanoic Acid-Disturbed Serum and Liver Lipidome in C57BL/6 Mice.  |  Gao, B., et al. 2022. Chem Res Toxicol. 35: 2252-2259. PMID: 36484463

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Pentadecafluorooctanoic acid, 5 g

sc-250662
5 g
$49.00

Pentadecafluorooctanoic acid, 25 g

sc-250662A
25 g
$149.00