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Penicillin V Potassium (CAS 132-98-9)

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Alternate Names:
Phenoxymethylpenicillinic acid potassium salt; Antibiocin; Beromycin; Cliacil
Application:
Penicillin V Potassium is a bactericidal agent
CAS Number:
132-98-9
Purity:
≥98%
Molecular Weight:
388.48
Molecular Formula:
C16H17N2O5S•K
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Penicillin V Potassium is an antibiotic derived from penicillin and is semi-synthetic in nature. Additionally, this compound finds extensive utility in scientific research. The mechanism of action of Penicillin V Potassium involves inhibiting the synthesis of the bacterial cell wall. It achieves this by binding to the enzyme transpeptidase, which plays a role in peptidoglycan formation—an essential component of the bacterial cell wall. Through this interaction, Penicillin V Potassium hinders the enzyme′s function, preventing the creation of new peptidoglycan. Consequently, bacterial cells are unable to sustain their cell walls, leading to their demise.


Penicillin V Potassium (CAS 132-98-9) References

  1. Stability of penicillin V potassium in unit dose oral syringes.  |  Grogan, LJ., et al. 1979. Am J Hosp Pharm. 36: 205-8. PMID: 105635
  2. Stability of oral liquid penicillins in unit dose containers at various temperatures.  |  Allen, LV. and Lo, P. 1979. Am J Hosp Pharm. 36: 209-11. PMID: 105636
  3. Disseminated Osteomyelitis Caused by Clostridium novyi in a Cat.  |  Dunn, JK., et al. 1983. Can Vet J. 24: 312-5. PMID: 17422318
  4. Water-immiscible room temperature ionic liquids (RTILs) as drug reservoirs for controlled release.  |  Jaitely, V., et al. 2008. Int J Pharm. 354: 168-73. PMID: 18342462
  5. Quantum chemical studies on the inhibition potentials of some Penicillin compounds for the corrosion of mild steel in 0.1 M HCl.  |  Eddy, NO. and Ebenso, EE. 2010. J Mol Model. 16: 1291-306. PMID: 20112037
  6. Liquid chromatographic determination of penicillin V potassium in tablets: collaborative study.  |  Mopper, B. 1989. J Assoc Off Anal Chem. 72: 883-4. PMID: 2512278
  7. Insufficient evidence of the effect of systemic antibiotics on adults with symptomatic apical periodontitis or acute apical abscess.  |  Veitz-Keenan, A. and De Bartolo, AM. 2014. Evid Based Dent. 15: 104-5. PMID: 25522939
  8. Liquid chromatographic determination of penicillin V potassium in tablets and powders for oral solution.  |  Mopper, B. 1987. J Assoc Off Anal Chem. 70: 39-41. PMID: 3104305
  9. Isolation, Screening, and Characterization of Antibiotic-Degrading Bacteria for Penicillin V Potassium (PVK) from Soil on a Pig Farm.  |  Yang, X., et al. 2019. Int J Environ Res Public Health. 16: PMID: 31248086
  10. Appropriateness of Therapeutic Antibiotic Prescriptions by Lebanese Dentists in the Management of Acute Endodontic Abscesses.  |  Al Asmar Ramli, G., et al. 2020. Cureus. 12: e7327. PMID: 32313768
  11. Structure and function response of bacterial communities towards antibiotic contamination in hyporheic zone sediments.  |  Zhang, L., et al. 2022. Chemosphere. 309: 136606. PMID: 36174729
  12. Penicillin V therapy for streptococcal pharyngitis: comparison of dosage schedules.  |  Spitzer, TQ. and Harris, BA. 1977. South Med J. 70: 41-2. PMID: 402697
  13. The bioavailability of oral penicillin V. A comparative study of the absorption of different salts of penicillin V in children.  |  Bolme, P. and Eriksson, M. 1976. Acta Paediatr Scand. 65: 253-6. PMID: 816174
  14. Bactericidal activities of cefprozil, penicillin, cefaclor, cefixime, and loracarbef against penicillin-susceptible and -resistant Streptococcus pneumoniae in an in vitro pharmacodynamic infection model.  |  Cappelletty, DM. and Rybak, MJ. 1996. Antimicrob Agents Chemother. 40: 1148-52. PMID: 8723456
  15. Treatment of acute otitis media with a shortened course of antibiotics: a meta-analysis.  |  Kozyrskyj, AL., et al. 1998. JAMA. 279: 1736-42. PMID: 9624028

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Penicillin V Potassium, 10 g

sc-204839
10 g
$47.00

Penicillin V Potassium, 25 g

sc-204839A
25 g
$76.00